213403-03-3Relevant academic research and scientific papers
DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE
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Page/Page column 26, (2009/07/18)
The present invention is related to a compound of formula (I): wherein i, j, n, o, p, q, r, R1a, R1b, R1c, R1d, R2a, R2b, R2c, R2d, R3a, R3b and R4 are as defined herein, or an addition salt with an acid thereof, or a hydrate or solvate thereof, its preparation, pharmaceutical composition, and uses for treating a disease in which the enzyme 11β-HSD1 is involved.
Syntheses of thieno[2,3-b][1,4]thiazine, 1,4-benzoxazine and 1,4- benzothiazine derivatives with ion channel antagonistic activity
Schreder,Erker
, p. 75 - 85 (2007/10/03)
The syntheses of the thieno[2,3-b][1,4]thiazine derivatives 8 and 9 are described. Reaction of compound 4 with different acyl halides followed by substitution with various ethanamines gave the products 8 and 9. The new 3,4- dihydro-2H-1,4-benzoxazine deri
