213545-22-3

Basic information

• Product Name: rac-1-benzoyloxy-4-(tetrahydropyranyloxy)tetradec-2(E)-ene-5,8-diyne
• Synonyms: rac-1-benzoyloxy-4-(tetrahydropyranyloxy)tetradec-2(E)-ene-5,8-diyne
• CAS NO: 213545-22-3
• Molecular Weight: 408.538
• Mol File: 213545-22-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: rac-1-benzoyloxy-4-(tetrahydropyranyloxy)tetradec-2(E)-ene-5,8-diyne(CAS DataBase Reference)
• NIST Chemistry Reference: rac-1-benzoyloxy-4-(tetrahydropyranyloxy)tetradec-2(E)-ene-5,8-diyne(213545-22-3)
• EPA Substance Registry System: rac-1-benzoyloxy-4-(tetrahydropyranyloxy)tetradec-2(E)-ene-5,8-diyne(213545-22-3)

Safety Data

• Hazardous Substances Data: 213545-22-3(Hazardous Substances Data)

Upstream product

• 213545-10-9 rac-1-benzoyloxy-7-chlorohept-2(E)-en-5-yn-4-ol 
• 98-88-4 benzoyl chloride 
• 81121-63-3 4‐hydroxybut‐2‐en‐1‐yl benzoate 
• 118017-13-3 trans-benzoic acid 4-oxo-but-2-enyl ester 
• 118017-20-2 4-hydroxybut-2-yn-1-yl benzoate 
• 54339-95-6 1,4-bis-benzoyloxy-but-2-yne 
• 110-87-2 3,4-dihydro-2H-pyran 
• 213545-21-2 rac-1-(benzoyloxy)tetradec-2(E)-ene-5,8-diyn-4-ol 

Relevant articles and documents

Synthetic research on hepoxilins. 7.* Divergent total synthesis of hepoxilins and related eicosanoids

A new synthetic strategy for hydroxy-epoxy eicosanoids formed through the lipoxygenase pathway is developed. It makes use of a single synthon of the central functionalized fragment of the target molecules, namely racemic (E)-CICH2C≡CCHOHCH=CHCH2OBz. Elongation of the carbon chain of the synthon by successive condensations at both ends altenatively with hept-1-yne and hex-5-ynoic acid followed by enantioselective double bond epoxidation and partial hydrogenation of the triple bonds resulted in the syntheses of hepoxilins B3, their potential 8-lipoxygenase analogs, or their enantiomers, depending on the sequence of carbon chain elongations and the chirality of the epoxidation controller used.