118017-13-3Relevant articles and documents
4-(Dimethylamino)pyridinium Chlorochromate, a New Selective Reagent for the Oxidation of Allylic and Benzylic Alcohols
Guziec, Frank S.,Luzzio, Frederick A.
, p. 1787 - 1789 (1982)
4-(Dimethylamino)pyridinium chlorochromate (3) is a mild selective reagent for the oxidation of complex allylic and benzylic alcohols to the corresponding carbonyl compounds.
Total syntheses of melodienones by redox isomerization of propargylic alcohols
Dong, Chunmao,Peng, Weiwei,Wang, Huan,Zhang, Xiao,Zhang, Jun,Tan, Guishan,Xu, Kangping,Zou, Zhenxing,Tan, Haibo
, p. 5077 - 5081 (2021/06/21)
A remarkable base-promoted methodology for the rapid construction of the (E)- and (Z)-γ-oxo-α,β-alkenoic ester skeletons from readily accessible vinyl propargylic alcohols through modified redox isomerization was uncovered. This approach manifested its hi
Sequencing cross-metathesis and non-metathesis reactions to rapidly access building blocks for synthesis
Sirasani, Gopal,Paul, Tapas,Andrade, Rodrigo B.
experimental part, p. 2197 - 2205 (2011/04/22)
The olefin cross-metathesis reaction has been sequenced with four common organic transformations in a one- or two-pot manner to rapidly access useful building blocks. Those reactions are: (1) phosphorus-based olefination (e.g., Wittig and Horner-Wadsworth-Emmons); (2) hydride reduction; (3) Evans propionate aldol reaction; (4) Brown allyl- and Roush crotyl-boration. The products of these reactions include stereodefined 2,4-dienoates, trans allylic alcohols, syn-propionate aldols, and chiral non-racemic homoallylic alcohols, respectively. Many of these intermediates have been carried further to natural products, demonstrating the utility of the methodology.
