213548-88-0Relevant articles and documents
Nucleotides. Part LXVIII. Acetals as New 2'-O-Protecting Functions for the Synthesis of Oligoribonucleotides: Synthesis of Monomeric Building Units and Oligoribonucleotides
Matysiak, Stefan,Pfleiderer, Wolfgang
, p. 1066 - 1085 (2007/10/03)
For the efficient synthesis of oligoribonucleotides by the 5'-O-(4,4'-dimethoxytrityl) phosphoramidite approach, the 2'-O-[1-(benzyloxy)ethyl]acetals 56-67 were investigated. Studies with the 2'-O-[1-(benzyloxy)ethyl]-5'-O-(dimethoxytrityl)ribonucleoside
Solid-phase synthesis of oligoribonucleotides
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, (2008/06/13)
A process for the preparation of oligoribonucleotides of the formula STR1 in which n, L, BB, W, T, Y', U, C1 and C2 are as defined in the description, by solid-phase synthesis is described, as are intermediates of the oligoribonucleo