213623-90-6

Basic information

• Product Name: (Z)-4-benzylidene-1-methyl-1,4-dihydro-2H-3,1-benzoxazine-2-one
• Synonyms: (Z)-4-benzylidene-1-methyl-1,4-dihydro-2H-3,1-benzoxazine-2-one
• CAS NO: 213623-90-6
• Molecular Weight: 251.285
• Mol File: 213623-90-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-4-benzylidene-1-methyl-1,4-dihydro-2H-3,1-benzoxazine-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4-benzylidene-1-methyl-1,4-dihydro-2H-3,1-benzoxazine-2-one(213623-90-6)
• EPA Substance Registry System: (Z)-4-benzylidene-1-methyl-1,4-dihydro-2H-3,1-benzoxazine-2-one(213623-90-6)

Safety Data

• Hazardous Substances Data: 213623-90-6(Hazardous Substances Data)

Upstream product

• 615-43-0 2-iodophenylamine 
• 536-74-3 phenylacetylene 
• 1421753-45-8 1,1-dimethylethyl N-methyl-N-[2-(2-phenylethynyl)phenyl]carbamate 
• 221353-36-2 1,1-dimethylethyl N-[2-(phenylethynyl)phenyl]carbamate 
• 13141-38-3 2-phenylethynylaniline 
• 124-38-9 carbon dioxide 
• 170956-92-0 N-methyl-2-(2-phenylethynyl)aniline 

Relevant articles and documents

Silver-catalyzed incorporation of carbon dioxide into o-alkynylaniline derivatives

Benzoxazine-2-one derivatives are important heterocycle structures because of their various pharmaceutical activities, though their synthetic methods had been limited. In some cases, toxic reagents, such as phosgene or carbon monoxide, are required. It was found that a silver catalyst successfully promoted the incorporation of CO2 into o-alkynylanilines to afford the corresponding benzoxazine-2-ones bearing Z exo-olefin via 6-exo-dig cyclization at the activated C-C triple bond.