213757-82-5

Basic information

• Product Name: (1R,2S)-2-(Acetylamino-methyl)-cyclopropanecarboxylic acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester
• CAS NO: 213757-82-5
• Molecular Weight: 269.298
• Mol File: 213757-82-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S)-2-(Acetylamino-methyl)-cyclopropanecarboxylic acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-2-(Acetylamino-methyl)-cyclopropanecarboxylic acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester(213757-82-5)
• EPA Substance Registry System: (1R,2S)-2-(Acetylamino-methyl)-cyclopropanecarboxylic acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester(213757-82-5)

Safety Data

• Hazardous Substances Data: 213757-82-5(Hazardous Substances Data)

Upstream product

• 213757-85-8 (1S,2R)-2-(Acetylamino-methyl)-cyclopropanecarboxylic acid 
• 599-04-2 (R)-Pantolacton 

Downstream Products

• 215597-45-8 (+/-)-CAMP 

Relevant articles and documents

Resolution and conformational analysis of diastereoisomeric esters of cis- and trans-2-(aminomethyl)-1-carboxycyclopropanes

(1R,2S)-, (1S,2R)-, (1R,2R)- and (1S,2S)-2-(Aminomethyl)-1- carboxycyclopropanes, conformationally restricted analogues of the neurotransmitter γ-aminobutyric acid (GABA), have been resolved by chromatographic separation of the corresponding diastereoisomeric esters which were formed between the cis- and trans-2-(acetamidomethyl)1- carboxycyclopropanes with (R)-(-)-pantolactone. 1H NMR, semi-empirical conformational analysis, ab initio (DFT) structure and NMR shielding tensor calculations of the cis-diastereoisomers allowed the absolute configuration assignments of the cis-amino acids.