21377-09-3

Usage

Uses

Used in Pharmaceutical Industry:
1-Benzyl-1H-pyrazol-3-ylamine is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be incorporated into drug molecules, potentially enhancing their therapeutic effects and targeting specific biological pathways.
Used in Agrochemical Industry:
In the agrochemical sector, 1-benzyl-1H-pyrazol-3-ylamine is utilized as a building block in the development of crop protection agents. Its incorporation into these agents can lead to improved efficacy in protecting crops from pests and diseases, thereby contributing to increased agricultural productivity.
Used in Research and Development:
1-Benzyl-1H-pyrazol-3-ylamine is employed as a subject of research in the exploration of its biological activity and pharmacological properties. Scientists are investigating its potential uses in the development of new drugs and therapies, as well as its interactions with biological systems to better understand its mechanisms of action.

InChI:InChI=1/C10H11N3/c11-10-6-7-13(12-10)8-9-4-2-1-3-5-9/h1-7H,8H2,(H2,11,12)

Upstream product

• 72159-23-0 N-(1-benzyl-1H-pyrazol-3-yl)-phthalimide 
• 100-39-0 benzyl bromide 
• 898053-27-5 1-benzyl-3-nitro-1H-pyrazole 

Downstream Products

• 73498-44-9 2-Benzyl-6,7-dihydro-4-methyl-6-oxo-pyrazolo<3,4-b>pyridin 
• 92133-81-8 N-(1-benzyl-1H-pyrazol-3-yl)-toluene-4-sulfonamide 
• 104164-04-7 1-Benzyl-5-chloromethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one 
• 1142952-01-9 3-benzyloxy-N-(1-benzyl-1H-pyrazole-3-yl)-5-isopropoxy-benzamide 
• 1142952-02-0 N-(1-benzyl-1H-pyrazole-3-yl)-3-((S)-2-methoxy-1-methyl-ethoxy)-5-((S)-1-methyl-2-phenyl-ethoxy)-benzamide 
• 1142952-08-6 N-(1-benzyl-1H-pyrazol-3-yl)-3-isopropoxy-5-(2-thiophen-3-yl-ethoxy)-benzamide 
• 1612164-58-5 N²-(1-benzyl-1H-pyrazol-3-yl)-N₄-(1-isopropyl-1H-imidazo[4,5-c]pyridin-6-yl)pyrimidine-2,4-diamine 

Relevant academic research and scientific papers

Synthesis and properties of 1-[(adamantan-1-yl)methyl]-3-pyrazolyl ureas

[Figure not available: see fulltext.] A series of 1,3-disubstituted ureas containing 1,3,5-trisubstituted pyrazole and (adamantan-1-yl)methyl fragments were synthesized in the reaction of 1-(isocyanatomethyl)adamantane with 3- or 4-aminopyrazoles under mi

SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME

ABSTRACT The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.

(PYRAZOL-3-YL)-1,3,4-THIADIAZOL-2-AMINE AND (PYRAZOL-3-YL)-1,3,4-THIAZOL-2-AMINE COMPOUNDS

A compound of Formula (I) wherein: either X is N and Y is CR5 or X is C and Y is S; Z is selected from N and CH; R1 is selected from H and Me; R2 is selected from H, OH, OMe and Me; each R3 is independently selected from C1-3alkyl, F, Cl, Br, CF3 and NH2; R4 is selected from Me, CF3, NO2 and CHF2; R5 is selected from H, Me and CHF2; R6 is selected from H and Me; and p is 0-3, compositions containing them, their use in therapy, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.

N- ( PYRAZOLE- 3 -YL) -BENZAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS

Novel heterocyclic compounds of the formula (I) in which R1, R2, R3, R4, R5, R6, R7, Alk and D have the meanings indicate in Claim 1, are activators of glucokinase and can be used for the prevention and/or treatment of Diabetes Typ 1 and 2, obesity, neuropathy and/or nephropathy.

Pyrazole glucokinase activators

Disclosed herein are pyrazole glucokinase activators of the formula (I) useful for the treatment of metabolic diseases and disorders, preferably diabetes mellitus.

Substituted 1H-pyrazolo (1,5-a) pyrimidines and process for their preparation

Compounds of general formula (I) STR1 wherein R1 is a 2-pyridyl, 3-pyridyl or 4-pyridyl group; (b) a phenyl ring, unsubstituted or substituted by one or two groups chosen from halogen, trihalo-C1 -C4 alkyl, C1 -