213776-05-7

Basic information

• Product Name: 1,2-Ethanediol, 1,2-bis(4-bromophenyl)-, (1R,2R)-
• CAS NO: 213776-05-7
• Molecular Formula: C14H12Br2O2
• Molecular Weight: 372.056
• Mol File: 213776-05-7.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,2-Ethanediol, 1,2-bis(4-bromophenyl)-, (1R,2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Ethanediol, 1,2-bis(4-bromophenyl)-, (1R,2R)-(213776-05-7)
• EPA Substance Registry System: 1,2-Ethanediol, 1,2-bis(4-bromophenyl)-, (1R,2R)-(213776-05-7)

Safety Data

• Hazardous Substances Data: 213776-05-7(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 
• 18869-30-2 (E)-4,4'-dibromostilbene 
• 589-87-7 1,4-bromoiodobenzene 
• 35578-47-3 4,4'-dibromobenzil 
• 97-72-3 2-Methylpropionic anhydride 

Downstream Products

• 52340-78-0 (R,R)-hydroxybenzoin 
• 873297-79-1 (1R,2R)-1,2-bis(4'-bromophenyl)-1,2-dimethoxyethane 
• 925899-71-4 (4R,5R)-4,5-bis-(4-bromophenyl)-2,2-dimethyl-1,3-dioxolane 
• 925899-70-3 (S,S)-4,5-di(4-carboxyphenyl)-2,2-dimethyl-[1,3]dioxolane 

Relevant articles and documents

Hydrogen Bonding-Assisted Enhancement of the Reaction Rate and Selectivity in the Kinetic Resolution of d,l-1,2-Diols with Chiral Nucleophilic Catalysts

An extremely efficient acylative kinetic resolution of d,l-1,2-diols in the presence of only 0.5 mol% of binaphthyl-based chiral N,N-4-dimethylaminopyridine was developed (selectivity factor of up to 180). Several key experiments revealed that hydrogen bonding between the tert-alcohol unit(s) of the catalyst and the 1,2-diol unit of the substrate is critical for accelerating the rate of monoacylation and achieving high enantioselectivity. This catalytic system can be applied to a wide range of substrates involving racemic acyclic and cyclic 1,2-diols with high selectivity factors. The kinetic resolution of d,l-hydrobenzoin and trans-1,2-cyclohexanediol on a multigram scale (10 g) also proceeded with high selectivity and under moderate reaction conditions: (i) very low catalyst loading (0.1 mol%); (ii) an easily achievable low reaction temperature (0 °C); (iii) high substrate concentration (1.0 M); and (iv) short reaction time (30 min). (Figure presented.).

Stereoselective synthesis of optically active hydrobenzoins via asymmetric hydrogenation of benzils with Ru(OTf)(TsDPEN)(I·6- cymene) as the pre-catalyst

Optically active hydrobenzoins are very important building blocks for further derivation of biologically active complexes, natural products, and pharmaceutical compounds. In this paper, A practical approach has been developed for asymmetric hydrogenation

Lanthanitin: A chiral nanoball encapsulating 18 lanthanum ions by ferritin-like assembly

(Figure Presented) A chiral supramolecule, obtained by self-assembly of 24 chiral ditopic carboxylate ligands, 18 La ions, and two carbonate anions, has been dubbed lanthanitin because of its structural resemblance to ferritin. The picture shows the molec