213776-97-7Relevant articles and documents
Inter- and intramolecular alcohol additions to exo-glycals
Chang, Chuan-Fa,Yang, Wen-Bin,Chang, Che-Chien,Lin, Chun-Hung
, p. 6515 - 6519 (2002)
Various exo-glycals were explored for the glycosidic bond formation and synthesis of spiroacetals in a stereoselective manner. The former reaction was an intermolecular alcohol addition to give the S new stereogenic center, resulting from the nucleophilic
Synthesis and elaboration of functionalised carbohydrate-derived spiroketals
Van Hooft, Peter A. V.,Oualid, Farid El,Overkleeft, Herman S.,Van der Marel, Gijsbert A.,Van Boom, Jacques H.,Leeuwenburgh, Michiel A.
, p. 1395 - 1403 (2007/10/03)
The scope of a stereoselective three-step approach for the synthesis of sugar derived spiroketals is presented. The methodology consists of Grignard addition of vinyl- or allylmagnesium bromide to a carbohydrate lactone, followed by K-10 clay mediated gly
A novel and flexible synthesis of pyranose spiroacetal derivatives
Van Hooft, Peter A. V.,Leeuwenburgh, Michiel A.,Overkleeft, Herman S.,Van Der Marel, Gijsbert A.,Van Boeckel, Constant A. A.,Van Boom, Jacques H.
, p. 6061 - 6064 (2007/10/03)
A three-step approach to chiral pyranose [5,4], [5,5], [5,6] and [5,7] unsaturated spiroacetal derivatives from perbenzylated glucopyranolactone 1 is presented. The strategy involves Grignard addition of vinyl or allyl magnesium bromide to 1 to give 2 and