213815-23-7

Upstream product

• 78606-78-7 methyl (E,5S,6R)-5,6,7-trihydroxyhept-2-enoate 
• 22900-10-3 2-deoxy-D-ribose 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 250226-93-8 (E)-4-((2R,4S,5R)-5-Hydroxy-2-phenyl-[1,3]dioxan-4-yl)-but-2-enoic acid methyl ester 

Downstream Products

• 213815-40-8 (2R,4aR,6S,7R,9aS)-7-(tert-Butyl-dimethyl-silanyloxy)-7-methyl-2-phenyl-6-triethylsilanyloxymethyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocycloheptene 
• 213815-45-3 tert-Butyl-[(2R,4aR,6S,7R,9aS)-6-((1Z,3Z)-hepta-1,3,6-trienyl)-7-methyl-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-7-yloxy]-dimethyl-silane 
• 213815-42-0 tert-Butyl-[(2R,4aR,6S,7R,9aS)-6-(2,2-dibromo-vinyl)-7-methyl-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-7-yloxy]-dimethyl-silane 
• 213815-39-5 (2R,4aR,6S,7R,9aS)-7-Methyl-2-phenyl-6-triethylsilanyloxymethyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-7-ol 
• 213815-34-0 (2R,4aR,6S,7R,9aS)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-2-phenyl-hexahydro-1,3,5-trioxa-benzocyclohepten-7-ol 
• 213815-43-1 [(2R,4aR,6S,7R,9aS)-6-((Z)-2-Bromo-vinyl)-7-methyl-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-7-yloxy]-tert-butyl-dimethyl-silane 
• 213815-37-3 (2R,4aR,6S,7R,9aS)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-7-methyl-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-7-ol 
• 213815-41-9 [(2R,4aR,6S,7R,9aS)-7-(tert-Butyl-dimethyl-silanyloxy)-7-methyl-2-phenyl-4a,6,7,9a-tetrahydro-4H-1,3,5-trioxa-benzocyclohepten-6-yl]-methanol 
• 213815-35-1 (2R,4aR,6S,9aS)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-2-phenyl-tetrahydro-1,3,5-trioxa-benzocyclohepten-7-one 
• 213815-28-2 [3-((2R,4S,5R)-5-Allyloxy-2-phenyl-[1,3]dioxan-4-yl)-propoxy]-tert-butyl-dimethyl-silane 
• 213815-36-2 (2R,4aR,6S,9aS)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-2-phenyl-4a,9a-dihydro-4H-1,3,5-trioxa-benzocyclohepten-7-one 
• 213815-27-1 (2R,4S,5R)-4-[3-(tert-Butyl-dimethyl-silanyloxy)-propyl]-2-phenyl-[1,3]dioxan-5-ol 
• 213815-25-9 3-[(2R,4S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-[1,3]dioxan-4-yl]-propan-1-ol 
• 213815-33-9 (2R,4aR,6S,7R,9aS)-6-Hydroxymethyl-2-phenyl-hexahydro-1,3,5-trioxa-benzocyclohepten-7-ol 

Relevant academic research and scientific papers

Total synthesis of brevetoxin A: Part 2: Second generation strategy and construction of EFGH model system

Our second generation strategy for the total synthesis of brevetoxin A involved dissection of the molecule at the ring F oxocene. Synthetically, the F ring formation was expected to occur through Wittig coupling of requisite polycyclic fragments 2 and 3,