21386-00-5Relevant academic research and scientific papers
Method for synthesizing aromatic ring-containing alpha-hydroxyphosphonate through copper catalysis
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Paragraph 0039-0041, (2020/05/01)
The invention relates to a method for synthesizing aromatic ring-containing alpha-hydroxyphosphonate through copper catalysis. The method comprises the following steps: dissolving diethyl phosphite and aromatic aldehyde in an organic solvent, adding a cop
Hydrophosphonylation of aldehydes catalyzed by cyclopentadienyl ruthenium(II) complexes
Cabrita, Ivania R.,Florindo, Pedro R.,Costa, Paulo J.,Oliveira, M. Concei??o,Fernandes, Ana C.
, p. 77 - 86 (2018/03/22)
This work reports the first method for the synthesis of α-hydroxyphosphonates from aldehydes catalyzed by cyclopentadienyl ruthenium(II) complexes. The best results were obtained using the system HP(O)(OEt)2/[RuClCp(PPh3)2
Cholic acid-alpha-amino phosphonate derivative and synthesis method thereof
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Paragraph 0015; 0016; 0026; 0030, (2016/10/09)
The invention belongs to the field of medicine chemistry and particularly relates to a cholic acid-alpha-amino phosphonate derivative and a preparation method thereof.Cholic acid and phosphate ester serve as raw materials, and the cholic acid-alpha-amino
Bile acid-alpha-hydroxyphosphonate derivatives and synthetic method thereof
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Paragraph 0017; 0018; 0020; 0024, (2016/12/22)
The invention belongs to the field of pharmaceutical chemistry and particularly relates to novel bile acid-alpha-hydroxyphosphonate compounds and a preparation method thereof. Bile acid and phosphate ester are taken as raw materials, the bile acid-alpha-h
Syntheses of bimetallic rare-earth bis(cyclopentadienyl) derivatives supported by bridged bis(guanidinate) ligands and their catalytic property for the hydrophosphonylation of aldehydes
Nie, Kun,Liu, Chengwei,Zhang, Yong,Yao, Yingming
, p. 59 - 65 (2016/01/15)
Some bimetallic rare earth bis(cyclopentadienyl) derivatives supported by bridged bis(guanidinate) ligands {(C5H5)2RE[(RN)2CN(CH2)2]}2 [R = iPr, RE = Yb(1), Er(2), Y(3
Preparation method of phosphonate derivative containing amino acid fragments and antineoplastic application
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Paragraph 0022, (2016/10/10)
The invention discloses a preparation method of a phosphonate derivative (I) containing amino acid fragments and antineoplastic application thereof, and belongs to the field of anticancer drug research. By adopting a drug discovery method based on fragmen
Ultrasound assisted green synthesis of α-hydroxyphosphonates under solvent-free conditions
Bouzina, Abdeslem,Aouf, Nour-eddine,Berredjem, Malika
, p. 5993 - 6002 (2016/06/01)
Abstract: A simple, efficient and environmentally benign method for the synthesis of α-hydroxyphosphonates by reaction of an aldehyde or a ketone, and trialkylphosphite is effectively accomplished under ultrasound irradiation and solvent-free and catalyst
Synthesis and characterization of ytterbium guanidinates stabilized by bridged bis(phenolate) ligand and their application for the hydrophosphonylation reaction of aldehydes
Zeng, Tinghua,Qian, Qinqin,Wang, Yaorong,Yao, Yingming,Shen, Qi
, p. 14 - 20 (2015/02/18)
A series of ytterbium guanidinato complexes stabilized by an amine-bridged bis(phenolate) ligand were prepared, and their catalytic property for the hydrophosphonylation reaction of aldehydes was explored. Metathesis reactions of amine-bridged bis(phenola
Syntheses of bimetallic lanthanide bis(amido) complexes stabilized by bridged bis(guanidinate) ligands and their catalytic activity toward the hydrophosphonylation reaction of aldehydes and ketones
Nie, Kun,Liu, Chengwei,Zhang, Yong,Yao, Yingming
, p. 1451 - 1460 (2015/09/02)
A series of bimetallic lanthanide bis(amido) complexes stabilized by bridged bis(guanidinate) ligands {[(Me3Si)2N]2Ln[(RN)2-CN(CH2)2]}2 [R= i Pr, Ln=Sm (1), Yb (2), Y
Synthesis of diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates
Makarov, Mikhail V.,Skvortsov, Evgenii A.,Brel, Valery K.
, p. 232 - 233 (2015/06/17)
The Kabachnik-Fields reaction of 4-piperidone hydrochloride monohydrate, an aromatic aldehyde and triethyl phosphite in the presence of triethylamine and magnesium perchlorate affords diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates in moderate yield
