21390-25-0

Basic information

• Product Name: 2,6-DIMETHOXY-P-XYLENE
• Synonyms: 2,6-DIMETHOXY-P-XYLENE
• CAS NO: 21390-25-0
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.22
• Mol File: 21390-25-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 239.1°C at 760 mmHg
• Flash Point: 87.5°C
• Appearance: /
• Density: 0.977g/cm³
• Vapor Pressure: 0.063mmHg at 25°C
• Refractive Index: 1.491
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2,6-DIMETHOXY-P-XYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIMETHOXY-P-XYLENE(21390-25-0)
• EPA Substance Registry System: 2,6-DIMETHOXY-P-XYLENE(21390-25-0)

Safety Data

• Hazardous Substances Data: 21390-25-0(Hazardous Substances Data)

Usage

General Description

2,6-DIMETHOXY-P-XYLENE, also known as DMPX, is a chemical compound that belongs to the family of aromatic hydrocarbons. It is commonly used as a solvent in various industrial and commercial applications, including in the production of paints, coatings, adhesives, and dyes. DMPX is also used as an intermediate in the manufacturing of pharmaceuticals and agrochemicals. It is a colorless liquid with a sweet odor and is flammable in nature. DMPX is considered to have low toxicity, but exposure to high concentrations can cause irritation to the respiratory system, skin, and eyes. Proper handling and storage procedures should be followed to ensure safe use of this chemical.

InChI:InChI=1/C10H14O2/c1-7-5-9(11-3)8(2)10(6-7)12-4/h5-6H,1-4H3

Upstream product

• 6443-69-2 3,4,5-trimethoxytoluene 
• 74-88-4 methyl iodide 
• 4179-19-5 1,3-dimethoxy-5-methylbenzene 

Downstream Products

• 855954-88-0 1-(2-hydroxy-4-methoxy-3,6-dimethyl-phenyl)-heptadecan-1-one 
• 60441-79-4 methyl 3,5-dimethoxy-4-methylbenzoate 
• 162411-67-8 2-methyl-5-phenethylbenzene-1,3-diol 
• 1361954-86-0 5-(deuteriomethyl)-1,3-dimethoxy-2-methylbenzene 
• 488-87-9 2,5-dimethyl-1,3-benzenediol 
• 859782-46-0 2-Heptadecyl-5-methoxy-3,6-dimethyl-phenol 
• 39581-38-9 (2,4-dimethoxy-3,6-dimethyl-phenyl)-(3-methoxy-2,5-dimethyl-phenyl)-ether 
• 807628-69-9 3-cyano-4,6-dimethoxy-2,5-dimethylbenzaldehyde 
• 807628-78-0 3-dibromo-4,6-dimethoxy-2,5-dimethylbenzonitrile 
• 807628-84-8 3-dibromo-4,6-dimethoxy-2,5-dimethylbenzaldehyde 
• 807628-74-6 1,3-dibromo-4,6-dimethoxy-2,5-dimethylbenzene 
• 61040-81-1 4-methyl-3,5-dimethoxybenzoic acid 

Relevant articles and documents

Monocyclic Quinone Structure-Activity Patterns: Synthesis of Catalytic Inhibitors of Topoisomerase II with Potent Antiproliferative Activity

The monocyclic 1,4-benzoquinone, HU-331, the direct oxidation product of cannabidiol, inhibits the catalytic activity of topoisomerase II but without inducing DNA strand breaks or generating free radicals, and unlike many fused-ring quinones exhibits minimal cardiotoxicity. Thus, monocyclic quinones have potential as anticancer agents, and investigation of the structural origins of their biological activity is warranted. New syntheses of cannabidiol and (±)-HU-331 are here reported. Integrated synthetic protocols afforded a wide range of polysubstituted resorcinol derivatives; many of the corresponding novel 2-hydroxy-1,4-benzoquinone derivatives are potent inhibitors of the catalytic activity of topoisomerase II, some more so than HU-331, whose monoterpene unit replaced by a 3-cycloalkyl unit conferred increased antiproliferative properties in cell lines with IC50 values extending below 1 mM, and greater stability in solution than HU-331. The principal pharmacophore of quinones related to HU-331 was identified. Selected monocyclic quinones show potential for the development of new anticancer agents.

New Drug Delivery System for Crossing the Blood Brain Barrier

New ubiquinol analogs are disclosed, as well as methods of using these compounds to deliver drug moieties to the body.