213964-90-0

Upstream product

• 6893-26-1 D-Glutamic acid 
• 147200-10-0 (3S,5R)-dihydro-5-hydroxymethyl-3-methyl-2(3H)-furanone 
• 147093-44-5 3S,5R-5-azidomethyl-3-methyl-4,5-dihydro-2(3H)-furanone 
• 147093-40-1 3S,5R-5-mesyloxymethyl-3-methyl-4,5-dihydro-2(3H)-furanone 
• 147200-08-6 (3S,5R)-5-(tert-butyldiphenylsilyloxymethyl)-3-methyl-dihydrofuran-2(3H)-one 
• 213964-84-2 3-((6S,7R)-6,7-Dimethyl-7-vinyl-1,4-dioxa-spiro[4.5]dec-6-yl)-propionic acid methyl ester 
• 213964-89-7 ((2R,4S)-2-Hydroxy-4-methyl-5-phenylsulfanyl-pentyl)-carbamic acid benzyl ester 
• 213964-86-4 3-{(6S,7R)-7-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-6,7-dimethyl-1,4-dioxa-spiro[4.5]dec-6-yl}-propionic acid methyl ester 
• 213964-87-5 ((2R,4S)-4-Methyl-5-oxo-tetrahydro-furan-2-ylmethyl)-carbamic acid benzyl ester 
• 213964-85-3 3-[(6S,7R)-7-(2-Hydroxy-ethyl)-6,7-dimethyl-1,4-dioxa-spiro[4.5]dec-6-yl]-propionic acid methyl ester 
• 213964-88-6 ((2R,4S)-2,5-Dihydroxy-4-methyl-pentyl)-carbamic acid benzyl ester 
• 213964-82-0 3-((1S,2S)-2-Formyl-1,2-dimethyl-6-oxo-cyclohexyl)-propionic acid methyl ester 
• 1027966-69-3 (4aR,8aS)-4a,8a-Dimethyl-6-trimethylsilanyloxy-3,4,4a,7,8,8a-hexahydro-2H-naphthalen-1-one 
• 213964-83-1 3-((1S,2R)-1,2-Dimethyl-6-oxo-2-vinyl-cyclohexyl)-propionic acid methyl ester 

Downstream Products

• 213964-91-1 (R)-5-((S)-3-Benzenesulfonyl-6-{(6S,7R)-7-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-6,7-dimethyl-1,4-dioxa-spiro[4.5]dec-6-yl}-2-methyl-4-oxo-hexyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 213964-92-2 (R)-5-((S)-6-{(6S,7R)-7-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-6,7-dimethyl-1,4-dioxa-spiro[4.5]dec-6-yl}-2-methyl-4-oxo-hexyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 213964-78-4 (R)-5-[(S)-6-((6S,7R)-7-Carboxymethyl-6,7-dimethyl-1,4-dioxa-spiro[4.5]dec-6-yl)-2-methyl-4-oxo-hexyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Synthetic studies of zoanthamine/norzoanthamine: Biogenetic-like one-step construction of the heterocyclic aminal core (CDEFG ring) from a monocyclic precursor

Biogenetic-like one-step construction of the pentacyclic aminal core of zoanthamine/norzoanthamine alkaloids was accomplished in high yield from the suitably protected monocyclic aminohydroxy diketocarboxylic acid 7 by heating in aqueous acetic acid.

Synthetic studies of zoanthamine/norzoanthamine alkaloids: Advanced intermediate for the heterocyclic aminal core

An advanced intermediate for the heterocyclic aminal core of zoanthamine/norzoanthamine alkaloids was prepared in an enantio and stereoselective manner. Contiguous quaternary chiral centers were selectively constructed utilizing a stereoselective cuprate addition to the readily available (+)-Wieland-Miescher ketone.