21410-06-0

Basic information

• Product Name: 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE
• Synonyms: 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE
• CAS NO: 21410-06-0
• Molecular Formula: C₁₁H₈ClN₅
• Molecular Weight: 245.66772
• Product Categories: Heterocycle-Pyrimidine series
• Mol File: 21410-06-0.mol

Chemical Properties

• Boiling Point: 454.872 °C at 760 mmHg
• Flash Point: 228.898 °C
• Appearance: /
• Density: 1.506 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.749
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.98±0.30(Predicted)
• CAS DataBase Reference: 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE(21410-06-0)
• EPA Substance Registry System: 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE(21410-06-0)

Safety Data

• Hazardous Substances Data: 21410-06-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Benzyl-7-chloro-3H-[1,2,3]triazolo[4,5-d]pyrimidine is used as a pharmaceutical candidate for its potential antiviral and anticancer properties. Its unique structure and biological activities make it a promising compound for the development of new drugs to treat various diseases.
Used in Medicinal Chemistry Research:
3-Benzyl-7-chloro-3H-[1,2,3]triazolo[4,5-d]pyrimidine is used as a subject of study in medicinal chemistry research to explore its potential applications and mechanisms of action. Further investigation of this compound may lead to the discovery of new therapeutic agents and a better understanding of its role in biological processes.

InChI:InChI=1/C11H8ClN5/c12-10-9-11(14-7-13-10)17(16-15-9)6-8-4-2-1-3-5-8/h1-5,7H,6H2

Upstream product

• 21324-31-2 3-Benzyl-7-hydroxy-3H-1,2,3-triazolo<4,5-d>pyrimidine 
• 4342-08-9 4-amino-3-benzyl-1,2,3-triazole-5-carboxamide 
• 622-79-7 benzyl azide 
• 21324-31-2 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol 
• 100-39-0 benzyl bromide 

Downstream Products

• 13925-58-1 9-benzyl-8-azaadenine 

Relevant articles and documents

Cytoprotective activities of kinetin purine isosteres

Kinetin (N6-furfuryladenine), a plant growth substance of the cytokinin family, has been shown to modulate aging and various age-related conditions in animal models. Here we report the synthesis of kinetin isosteres with the purine ring replace

2,9-Disubstituted-N6-(arylcarbamoyl)-8-azaadenines as new selective A3 adenosine receptor antagonists: Synthesis, biochemical and molecular modelling studies

A number of N6-(N-arylcarbamoyl)-2-substituted-9-benzyl-8- azaadenines, obtained by a modification of the synthetic scheme used to prepare selective A1 ligands, by only three or two steps, are described. At first we prepared a series

Compounds containing a N-heteroaryl moiety linked to fused ring moieties for the inhibition of NAD(P)H oxidases and platelet activation

The invention relates to compounds containing a N-heteroaryl moiety, which is linked via oxygen, sulfur or nitrogen, or via a methylene bridge and oxygen, sulfur or nitrogen to a fused ring moiety, in particular to the 1,2,3-triazolo[4,5-d]pyrimidine-7-yl radical. The invention also relates to a process for the preparation of said compounds and the use thereof in drugs for the treatment of NAD(P)H oxidases-related diseases and disorders and inhibition of platelet activation.

Synthesis and plant growth regulating activity of new triazolo- and pyrazolopyrimidine derivatives of aminomethyl-, aminoalkyloxymethyl dimethylphosphine oxides and (aminomethane)phosphonic acid esters

New triazolo[4,5-d]pyrimidine and pyrazolo[3,4-d]pyrimidine derivatives of aminomethyl- and aminomethyloxymethyl dimethylphosphine oxides 8-14 as well as of esters of (aminomethane) phosphonic acid 18-20 were synthesized. The structure of the compounds prepared was confirmed by means of elemental analysis, IR, 1H- and 31P{1H}-NMR spectroscopy. Tertiary phosphine oxides 8, 9 and 12 as well as phosphonate 20 showed herbicidal and plant growth regulating activity.