21410-06-0

Basic information

• Product Name: 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE
• Synonyms: 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE
• CAS NO: 21410-06-0
• Molecular Formula: C₁₁H₈ClN₅
• Molecular Weight: 245.66772
• Product Categories: Heterocycle-Pyrimidine series
• Mol File: 21410-06-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 454.872 °C at 760 mmHg
• Flash Point: 228.898 °C
• Appearance: /
• Density: 1.506 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.749
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.98±0.30(Predicted)
• CAS DataBase Reference: 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE(21410-06-0)
• EPA Substance Registry System: 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE(21410-06-0)

Safety Data

• Hazardous Substances Data: 21410-06-0(Hazardous Substances Data)

Usage

General Description

3-Benzyl-7-chloro-3H-[1,2,3]triazolo[4,5-d]pyrimidine is a chemical compound that belongs to the triazolopyrimidine family. It is characterized by a benzene ring attached to the triazolo[4,5-d]pyrimidine core structure, along with a chlorine substituent at the 7th position. 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE is of interest in medicinal and pharmaceutical research due to its potential biological activities, including antiviral and anticancer properties. The unique structure of 3-benzyl-7-chloro-3H-[1,2,3]triazolo[4,5-d]pyrimidine makes it a valuable candidate for drug development and further study in the field of medicinal chemistry.

InChI:InChI=1/C11H8ClN5/c12-10-9-11(14-7-13-10)17(16-15-9)6-8-4-2-1-3-5-8/h1-5,7H,6H2

Upstream product

• 100-39-0 benzyl bromide 
• 21324-31-2 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol 
• 622-79-7 benzyl azide 
• 4342-08-9 4-amino-3-benzyl-1,2,3-triazole-5-carboxamide 
• 21324-31-2 3-Benzyl-7-hydroxy-3H-1,2,3-triazolo<4,5-d>pyrimidine 

Downstream Products

• 722456-31-7 (3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine) 
• 13925-58-1 9-benzyl-8-azaadenine 

Relevant articles and documents

Cytoprotective activities of kinetin purine isosteres

Kinetin (N6-furfuryladenine), a plant growth substance of the cytokinin family, has been shown to modulate aging and various age-related conditions in animal models. Here we report the synthesis of kinetin isosteres with the purine ring replace

Compounds containing a N-heteroaryl moiety linked to fused ring moieties for the inhibition of NAD(P)H oxidases and platelet activation

The invention relates to compounds containing a N-heteroaryl moiety, which is linked via oxygen, sulfur or nitrogen, or via a methylene bridge and oxygen, sulfur or nitrogen to a fused ring moiety, in particular to the 1,2,3-triazolo[4,5-d]pyrimidine-7-yl radical. The invention also relates to a process for the preparation of said compounds and the use thereof in drugs for the treatment of NAD(P)H oxidases-related diseases and disorders and inhibition of platelet activation.