214333-99-0

Upstream product

• 100-39-0 benzyl bromide 
• 857642-16-1 (2S,3R,4S,5R,6R)-2-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-(prop-2-yn-1-yloxy)tetrahydro-2H-pyran-3-yl]oxy}-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 

Downstream Products

• 214333-69-4 (2,3,4,6,3',6'-hepta-O-benzyl-β-D-lactopyranosyloxy)methylene acetate 
• 250127-82-3 allenyl 4-O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2',3',6'-tri-O-benzyl-β-D-glucopyranoside 
• 214333-71-8 1-[(2R,3R,4S,5R,6R)-3,4-Bis-benzyloxy-6-benzyloxymethyl-5-((2S,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-propan-2-one 

Relevant academic research and scientific papers

Study of metal and acid catalysed deprotection of propargyl ethers of alcohols via their allenyl ethers

A new method for the deprotection of prop-2-ynyl ethers 1b-9b is described. Isomerisation of 1b-9b to O-allenyl ethers 1d-9d and deprotection by reaction with Hg(OCOCF3)2, aq.HCl, aq.CF3CO2H and best by use of a catalytic amount of OsO4 is described to obtain the alcohols 1a-9a in good yield. Application of this method for the deprotection of prop-2-enyl ethers 7c,8c,10c-13c via their corresponding prop-1-enyl ethers 7e,8e,10e-13e to obtain the corresponding alcohols 7a,8a,10a-13a is also described.

Design, development and utility of glycosyl donors bearing an acetoxymethoxy leaving group

Novel glycosyl donors 2d, 4d and 6d bearing an 'acetoxy methoxy' leaving group have been prepared and their utility is shown by coupling them with alcohols A-G to obtain di- and trisaccharides by use of BF3-Et2O as a promoter.