250127-82-3

Upstream product

• 214333-99-0 prop-2-ynyl 4-O-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2',3',6'-tri-O-benzyl-β-D-glucopyranoside 
• 100-39-0 benzyl bromide 

Downstream Products

• 115988-74-4 2,3,6-tri-O-benzyl-4-O-(2′,3′,4′,6′-tetra-O-benzyl-β-D-galactopyranosyl)-D-glucopyranose 
• 214333-71-8 1-[(2R,3R,4S,5R,6R)-3,4-Bis-benzyloxy-6-benzyloxymethyl-5-((2S,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-propan-2-one 

Relevant academic research and scientific papers

Study of metal and acid catalysed deprotection of propargyl ethers of alcohols via their allenyl ethers

A new method for the deprotection of prop-2-ynyl ethers 1b-9b is described. Isomerisation of 1b-9b to O-allenyl ethers 1d-9d and deprotection by reaction with Hg(OCOCF3)2, aq.HCl, aq.CF3CO2H and best by use of a catalytic amount of OsO4 is described to obtain the alcohols 1a-9a in good yield. Application of this method for the deprotection of prop-2-enyl ethers 7c,8c,10c-13c via their corresponding prop-1-enyl ethers 7e,8e,10e-13e to obtain the corresponding alcohols 7a,8a,10a-13a is also described.