214336-16-0

Basic information

• Product Name: 4-(4-Fluoro-phenyl)-2-oxo-butyric acid isobutyl ester
• CAS NO: 214336-16-0
• Molecular Weight: 252.286
• Mol File: 214336-16-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-Fluoro-phenyl)-2-oxo-butyric acid isobutyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Fluoro-phenyl)-2-oxo-butyric acid isobutyl ester(214336-16-0)
• EPA Substance Registry System: 4-(4-Fluoro-phenyl)-2-oxo-butyric acid isobutyl ester(214336-16-0)

Safety Data

• Hazardous Substances Data: 214336-16-0(Hazardous Substances Data)

Upstream product

• 78-83-1 2-methyl-propan-1-ol 
• 85918-77-0 ethyl 4-(4-fluorophenyl)-2-oxobutanoate 
• 157977-55-4 (4-fluorophenylethyl)magnesium bromide 

Relevant articles and documents

Stereochemical control in microbial reduction. Part 31: Reduction of alkyl 2-oxo-4-arylbutyrates by baker's yeast under selected reaction conditions

Treatment of baker's yeast with phenacyl chloride in an aqueous-organic solvent has been proven to be an effective method of inhibiting the enzymes that afford (S)-enantiomers of α-hydroxy esters in the reduction of α-keto esters. The procedure is effective for the whole-cell system to produce the (R)-product with high chemical yield and high enantiomeric excess.