214417-22-8

Usage

Uses

Used in Medicinal Chemistry:
4-Chloro-2-phenylthieno[3,2-d]pyrimidine is used as a building block for the synthesis of various biologically active compounds due to its unique structure and properties.
Used in Pharmaceutical Industry:
4-Chloro-2-phenylthieno[3,2-d]pyrimidine is used as a target for drug discovery and development, with potential pharmacological activities that warrant further research to explore its full potential in various applications.

Upstream product

• 22288-78-4 Methyl 3-aminothiophene-2-carboxylate 
• 98-88-4 benzoyl chloride 
• 18678-14-3 2-phenyl-3H-thieno[3,2-d]pyrimidin-4-one 

Downstream Products

• 936837-30-8 C₂₀H₁₇N₃OS 
• 1201805-78-8 (S)-3-phenyl-2-(2-phenylthieno[3,2-d]pyrimidin-4-ylamino)propanoic acid 
• 1201805-72-2 4-chloro-6-iodo-2-phenylthieno[3,2-d]pyrimidine 
• 1201805-73-3 4-chloro-6,7-diiodo-2-phenylthieno[3,2-d]pyrimidine 
• 1043874-93-6 4-(2-phenyl-thieno[3,2-d]pyrimidin-4-yloxy)-benzonitrile 

Relevant academic research and scientific papers

Direct metallation of thienopyrimidines using a mixed lithium-cadmium base and antitumor activity of functionalized derivatives

A series of thieno[2,3-d]- and thieno[3,2-d]pyrimidines have been easily synthesized using as key step a deproto-cadmiation-trapping sequence. Some of the compounds thus synthesized were screened for anticancer (cytotoxic) activities, and (S)-2-(6-iodo-2-

Design, synthesis, and biological activities of new thieno[3,2- d]pyrimidines as selective type 4 phosphodiesterase inhibitors

A common pharmacophore for compounds structurally related to nitraquazone has been derived. Using this pharmacophore, new structures have been designed, synthesized, and evaluated for their inhibitory potencies against cyclic adenosine 5'-monophosphate (c