214541-34-1

Basic information

• Product Name: ethyl 1-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxylate
• Synonyms: ethyl 1-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxylate
• CAS NO: 214541-34-1
• Molecular Weight: 247.254
• Mol File: 214541-34-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: ethyl 1-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxylate(214541-34-1)
• EPA Substance Registry System: ethyl 1-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxylate(214541-34-1)

Safety Data

• Hazardous Substances Data: 214541-34-1(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 623-47-2 propynoic acid ethyl ester 
• 2101-87-3 p-methoxy-phenylazide 
• 12775-96-1 copper 

Downstream Products

• 1609428-44-5 N-(4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)butyl)-1-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide 
• 1609428-56-9 N-(2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl)-1-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide 
• 214541-38-5 1-(4-Methoxy-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid dimethylamide 
• 4916-13-6 1-(4-methoxyphenyl)-1H-[1,2,3]-triazolyl-4-carboxylic acid 

Relevant articles and documents

Alkyl Propiolates Participated [3+2] Annulation for the Switchable Synthesis of 1,5- and 1,4-Disubstituted 1,2,3-Triazoles Containing Ester Side Chain

By means of a featured enamine activation, the alkyl propiolates have been successfully employed in the [3+2] annulation for the synthesis of 1,2,3-triazoles. The synthesis of both 1,4- as well as the hardly available 1,5-disubstituted 1,2,3-triazoles can be selectively accessed by using tosyl azide and tosyl hydrazine as nitrogen source, respectively.

Synthesis and structure-activity relationship studies of conformationally flexible tetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands

Two novel classes of compounds targeting the sigma-2 (σ2) receptor were synthesized, and their bioactivities to binding σ1 and σ2 receptors were measured. Four novel triazole carboxamide analogues, 24d, 24e, 24f, and 39c, demonstrated high affinity and selectivity for the σ2 receptor. These data suggest 11C-labeled versions of these compounds may be potential σ2-selective radiotracers for imaging the proliferative status of solid tumors.

Heterogeneous copper catalyst for the cycloaddition of azides and alkynes without additives under ambient conditions

A new copper catalyst was developed by immobilizing copper nanoparticles in aluminum oxyhydoxide fiber. The catalyst showed high catalytic activity for the (3 + 2) Huisgen cycloaddition of nonactivated alkynes as well as activated ones with various azides