214626-85-4Relevant academic research and scientific papers
Synthesis of β-amino acids based on oxidative cleavage of dihydropyridone derivatives
Ege, Markus,Wanner, Klaus T.
, p. 3553 - 3556 (2007/10/03)
(Chemical Equation Presented) A new method for the synthesis of β-amino acids based on 2,3-dihydropyridones as starting materials is presented. Conversions of 2,3-dihydropyridones with NaIO4 and subsequently with base gave the corresponding β-amino acids in a one-pot procedure. The reactions have been monitored by 1H NMR indicating that the β-amino acids were formed in quantitative yields mostly. This method appears to be of broad scope, as 2-substituted 2,3-dihydropyridones are easily accessible via N-acyliminium ions generated from 4-methoxypyridine.
Solid phase synthesis of N-acyl-2-substituted-dihydro-4-pyridone: Resin activation/capture approach/REACAP technology
Chen, Chixu,Munoz, Benito
, p. 6781 - 6784 (2007/10/03)
Resin Activation/Capture (REACAP) Technology was used to prepare N- acyl-2-substituted-dihydro-4-pyridone analogs.
