214632-83-4

Upstream product

• 214632-80-1 Benzyl-((S)-2-hydroxy-1-methyl-but-3-enyl)-carbamic acid tert-butyl ester 
• 151929-50-9 ethyl (2E,4S)-4-[benzyl(tert-butoxycarbonyl)amino]pent-2-enoate 
• 31022-10-3 N-benzyl-L-alanine methyl ester 
• 100-39-0 benzyl bromide 
• 209266-07-9 methyl (S)-2-[(N-benzyl)-(N-t-butoxycarbonyl)amino]propanoate 
• 158380-71-3 tert-butyl (S)-benzyl(2-hydroxy-1-methylethyl)carbamate 
• 120205-98-3 tert-butyl (N)-benzyl(1-oxopropan-2-yl)carbamate 
• 361341-91-5 tert-butyl N-benzyl-N-[(1S,2E)-4-hydroxy-1-methyl-2-butenyl]carbamate 

Downstream Products

• 214632-86-7 (Z)-(4S,8S)-8-Benzylamino-non-6-en-4-ol 

Relevant academic research and scientific papers

Improved stereoselectivity in intramolecular SN2′ cyclization through use of mechanistic principles

Valine and alanine were converted into the corresponding α-hydroxy-β-amino acids through intramolecular SN2′ cyclization. The novel cyclization protocol relied upon the use of N-benzyl-protected carbamates derived from α-amino acids. Georg Thie

1,5-asymmetric induction in addition reaction of aldehydes with chiral allyltitaniums having an amino group at the stereogenic center. Synthesis of optically active 2,6-cis-disubstituted piperidines

Chiral allyltitaniums prepared from cyclic carbamate of optically active 4-aminoalk-1-en-3-ols and a Ti(O-i-Pr)4/2i-PrMgCl reagent react with aldehydes with good to excellent regio- and stereoselectivity to afford optically active 1.5-amino alcohols, from which optically active 2,6-cis- disubstituted piperidines are synthesized.