214632-86-7

Upstream product

• 123-72-8 butyraldehyde 
• 214632-83-4 3-benzyl-4-methyl-5-vinyloxazolidin-2-one 
• 214632-80-1 Benzyl-((S)-2-hydroxy-1-methyl-but-3-enyl)-carbamic acid tert-butyl ester 
• 209266-07-9 methyl (S)-2-[(N-benzyl)-(N-t-butoxycarbonyl)amino]propanoate 
• 120205-98-3 tert-butyl (N)-benzyl(1-oxopropan-2-yl)carbamate 
• 31022-10-3 N-benzyl-L-alanine methyl ester 
• 100-39-0 benzyl bromide 

Relevant academic research and scientific papers

1,5-asymmetric induction in addition reaction of aldehydes with chiral allyltitaniums having an amino group at the stereogenic center. Synthesis of optically active 2,6-cis-disubstituted piperidines

Chiral allyltitaniums prepared from cyclic carbamate of optically active 4-aminoalk-1-en-3-ols and a Ti(O-i-Pr)4/2i-PrMgCl reagent react with aldehydes with good to excellent regio- and stereoselectivity to afford optically active 1.5-amino alcohols, from which optically active 2,6-cis- disubstituted piperidines are synthesized.