214914-38-2

Upstream product

• 129227-54-9 1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carboxylic acid 
• 214914-34-8 1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carbonitrile 
• 614-16-4 Benzoylacetonitrile 
• 52943-85-8 5-amino-3-methyl-4-nitroso-1-phenylpyrazole 
• 214914-36-0 3-Methyl-1,6-diphenyl-1H-pyrazolo[3,4-b]pyrazine-5-carboxylic acid methyl ester 

Downstream Products

• 214914-44-0 1-Phenyl-4-(1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazin-5-oyl)thiosemicarbazide 
• 1593065-72-5 N'-benzoyl-1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carbohydrazide 
• 129227-48-1 1,6-diphenyl-3-methyl-5-(5-phenyl-1,3,4-oxadiazol-2-yl)-1H-pyrazolo[3,4-b]pyrazine 
• 1593065-71-4 N-(2,2-dimethyl-4-oxo-1,3-thiazolidin-3-yl)-1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carboxamide 
• 1593065-59-8 N-(2-phenyl-4-oxo-1,3-thiazolidin-3-yl)-1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carboxamide 
• 1593065-60-1 N-(2-(4-chlorophenyl)-4-oxo-1,3-thiazolidin-3-yl)-1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carboxamide 
• 1593065-62-3 N-(2-(4-nitrophenyl)-4-oxo-1,3-thiazolidin-3-yl)-1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carboxamide 
• 1593065-52-1 N'-(3,4-dimethoxybenzylidene)-1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carbohydrazide 
• 1593065-79-2 ethyl 2-(1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-oyl)hydrazine carboxylate 
• 1593065-77-0 1,6-diphenyl-N'-formyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carbohydrazide 
• 1593065-75-8 1,6-diphenyl-3-methyl-5-(1,3,4-oxadiazol-2-yl)-1H-pyrazolo[3,4-b]pyrazine 
• 1593065-45-2 1,6-diphenyl-3-methyl-N'-(prop-2-ylidene)-1H-pyrazolo[3,4-b]pyrazine-5-carbohydrazide 
• 1593065-68-9 N-(cyclohexane-spiro-2-(4-oxo-1,3-thiazolidin-3-yl))-1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carboxamide 
• 1593065-66-7 N-(cyclopentane-spiro-2-(4-oxo-1,3-thiazolidin-3-yl))-1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5-carboxamide 

Relevant academic research and scientific papers

Facile synthesis of some new pyrazolo [3,4-b] pyrazines and their antifungal activity

The synthesis of new pyrazolo [3,4-b] pyrazines and related heterocycles has been reported. The key intermediate 1,6-diphenyl-3-methyl-1H-pyrazolo[3,4-b]pyrazine-5- carbonitril 2 was obtained in one pot synthesis from the reaction of 5-amino-3-methyl-4-nitroso-1-phenylpyrazole 1 with benzoylacetonitrile. Modest antifungal activity was shown for some of the prepared compounds.