214915-69-2

Basic information

• Product Name: 4-BROMO-7-METHYLTRYPTOPHOL
• Synonyms: 4-BROMO-7-METHYLTRYPTOPHOL;2-(4-BROMO-7-METHYL-1H-INDOL-3-YL)ETHANOL;4-bromo-7-methyl-1H-Indole-3-ethanol
• CAS NO: 214915-69-2
• Molecular Formula: C₁₁H₁₂BrNO
• Molecular Weight: 283.16
• Mol File: 214915-69-2.mol

Chemical Properties

• Boiling Point: 417°C at 760 mmHg
• Flash Point: 206°C
• Appearance: /
• Density: 1.543g/cm³
• Vapor Pressure: 1.07E-07mmHg at 25°C
• Refractive Index: 1.678
• Storage Temp.: 2-8°C
• PKA: 14.83±0.10(Predicted)
• CAS DataBase Reference: 4-BROMO-7-METHYLTRYPTOPHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-7-METHYLTRYPTOPHOL(214915-69-2)
• EPA Substance Registry System: 4-BROMO-7-METHYLTRYPTOPHOL(214915-69-2)

Safety Data

• Hazardous Substances Data: 214915-69-2(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
4-BROMO-7-METHYLTRYPTOPHOL is used as a building block for the synthesis of new drugs. Its unique structure allows for the development of compounds with specific biological activities, making it a valuable asset in the field of medicinal chemistry.
Used in Drug Development:
4-BROMO-7-METHYLTRYPTOPHOL is used as a research tool in drug development. Its biological activity and interactions with biological pathways can provide insights into the design and optimization of new drugs targeting specific diseases or conditions.
Used in Research:
4-BROMO-7-METHYLTRYPTOPHOL is used in the study of biological pathways and processes involving tryptophol and its derivatives. Understanding the role of 4-BROMO-7-METHYLTRYPTOPHOL in biological systems can contribute to the advancement of knowledge in various fields, such as neuroscience, immunology, and cancer research.

InChI:InChI=1/C11H12BrNO/c1-7-2-3-9(12)10-8(4-5-14)6-13-11(7)10/h2-3,6,13-14H,4-5H2,1H3

Upstream product

• 1191-99-7 2,3-dihydro-2H-furan 
• 752200-75-2 (5-bromo-2-methylphenyl)hydrazine 
• 214915-68-1 4-[(5-bromo-2-methyl-phenyl)-hydrazono]-butan-1-ol 

Relevant articles and documents

Process for the scalable synthesis of 1,3,4,9-tetrahydropyrano[3,4-b]-indole derivatives

The invention is directed to a process of synthesizing compounds of formula (VI): wherein R1-R9, R3′, R4′ and Y are as set forth in the specification, and said method is useful for large scale synthesis thereof.

Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors

A novel series of HCV NS5B RNA-dependent RNA polymerase inhibitors containing a pyrano-[3,4-b]indole scaffold is described leading to the discovery of compound 16, a highly potent and selective inhibitor that is active in the replicon system.

METHOD FOR THE USE OF PYRANOINDOLE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS

The invention is directed to methods of treating, preventing, or inhibiting a Hepatitis C viral infection in a mammal comprising containing the mammal with an effective amount of a compound of the formula: Wherein substitutions at R1, R2, R3-R12, and Y are set forth in the specification.

R-ENANTIOMERS OF PYRANOINDOLE DERIVATIVES AGAINST HEPATITIS C

The invention is directed to a compound and a pharmaceutical composition of the formula: Wherein substitutions at R1, R2, R3 - R12, and Y are set forth in the specification.