214958-33-5

Usage

Uses

Used in Pharmaceutical Industry:
6-CYANO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER is used as an intermediate in the synthesis of potential antitumor, antiviral, and antibacterial agents. Its diverse biological activities make it a valuable component in the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
6-CYANO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER is also used as an intermediate in the synthesis of various agrochemical compounds, contributing to the development of effective solutions for pest control and crop protection.
Used in Research and Development:
6-CYANO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER is utilized in research and development for creating new drugs with enhanced therapeutic properties, as its unique structure and reactivity allow for the exploration of novel chemical pathways and potential applications in medicine and agriculture.

Upstream product

• 20511-12-0 2-amino-5-iodopyridine 
• 151-50-8 potassium cyanide 
• 214958-32-4 ethyl 6-iodo-1H-imidazo[1,2-a]pyridine-2-carboxylate 
• 4214-73-7 6-aminonicotinonitrile 
• 70-23-5 ethyl Bromopyruvate 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS

The compounds of Formula I, Formula Ia, and Formula Ib are described herein along with their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds inhibit PRMT5 and are useful as therpeautic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, Parkinson's disease and the like.

BASIC AMINE COMPOUND AND USE THEREOF

Novel amine compounds which are represented by the following formula (1) and efficacious against diseases such as a viral infectious disease with HIV, rheumatism, and cancer metastasis; typically, A 1 and A 2 represent a hydrogen atom or a substitutable monocyclic or polycyclic heteroaromatic ring and W represents a substitutable benzene ring or any group represented by the following formula (10) or (11): where X represents O, CH 2 , C(=O), NR 11 , or CHR 35 and D represents a group represented by the following formula (6): where Q represents a single bond, NR 12 , or a group represented by the formula (13): and Y represents a group represented by the following formula (7) : where z represents a substitutable monocyclic or polycyclic aromatic ring; and B represents -NR 25 R 26 ; and R 1 to R 26 in the above formulae represent a hydrogen atom, an alkyl group, an alkenyl group, or an alkynyl group.

Bis-cationic heteroaromatics as macrofilaricides: Synthesis of Bis- amidine and bis-guanylhydrazone derivatives of substituted imidazol[1,2- a]pyridines

A series of guanylhydrazone, amidine, and hydrazone derivatives of 2- phenylimidazo[1,2-a]-pyridine have been prepared and evaluated for macrofilarial activity against Acanthocheilonema viteae and Brugia pahangi in jirds. Compounds with 4',6-bis-substitut