214959-70-3

Upstream product

• 97250-25-4 tert-Butyldiphenylsilyl β-hydroxybutanone 
• 183378-05-4 trimethylsilyl ether of (1S,2S)-N-trifluoroacetamidonorpseudoephedrine 
• 762-72-1 allyl-trimethyl-silane 

Downstream Products

• 247256-57-1 (3R,1'S,2'S)-5-tert-Butyldiphenylsiloxy-3-methyl-3-(1'-phenyl-2'-trifluoroacetamido-1'-propoxy)-1-pentanal 
• 247256-58-2 (3R,5RS,1'S,2'S)-1-tert-Butyldiphenylsiloxy-3,7-dimethyl-3-(1'-phenyl-2'-trifluoroacetamido-1'-propoxy)-5-octanol 
• 247256-60-6 (3R,5RS)-1-tert-Butyldiphenylsiloxy-3,7-dimethyl-3,5-octanediol p-methoxybenzylidenacetal 
• 247256-59-3 (3R,5RS)-1-tert-Butyldiphenylsiloxy-3,7-dimethyl-3,5-octanediol 
• 247256-63-9 (4S,6RS)-4,8-Dimethyl-1-furan-3'-ylnonane-1-on-4,6-diol p-methoxybenzylideneacetal 
• 247256-62-8 (3R,5RS)-3,7-Dimethyl-1-iodo-3,5-octanediol p-methoxybenzylidenacetal 
• 247256-61-7 (3R,5RS)-3,7-Dimethyl-1,3,5-octanetriol-3,5-p-methoxybenzylidenacetal 
• 55626-95-4 athanagrandione 
• 340185-19-5 (E)-(4R,12S,13R)-7-(tert-Butyl-diphenyl-silanyloxy)-13-hydroxy-4-(4-methoxy-benzyloxy)-4,8,12-trimethyl-tetradec-8-enoic acid 
• 340185-20-8 (E)-(5R,8S,13S,14R)-8-(tert-Butyl-diphenyl-silanyloxy)-5-(4-methoxy-benzyloxy)-5,9,13,14-tetramethyl-oxacyclotetradec-9-en-2-one 
• 340185-25-3 (E)-(5R,8R,13S,14R)-8-(tert-Butyl-diphenyl-silanyloxy)-5-(4-methoxy-benzyloxy)-5,9,13,14-tetramethyl-oxacyclotetradec-9-en-2-one 
• 340185-22-0 (3E,9E)-(5R,8S,13S,14R)-8-(tert-Butyl-diphenyl-silanyloxy)-5-(4-methoxy-benzyloxy)-5,9,13,14-tetramethyl-oxacyclotetradeca-3,9-dien-2-one 
• 340185-23-1 (3E,9E)-(5R,8R,13S,14R)-8-(tert-Butyl-diphenyl-silanyloxy)-5-(4-methoxy-benzyloxy)-5,9,13,14-tetramethyl-oxacyclotetradeca-3,9-dien-2-one 
• 340185-18-4 (E)-(4R,12S,13R)-13-(tert-Butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-4,8,12-trimethyl-tetradeca-1,8-dien-7-ol 

Relevant academic research and scientific papers

Synthesis of enantiopure homoallylic alcohols by a highly selective asymmetric allylation of ketones

A highly selective asymmetric domino allytation of aliphatic ketones is described. When methyl ketones 1a-g, the chiral trimethylsilyl ether 2, and allylsilane 3 react in the presence of catalytic amounts of trifluoromethane-sulfonic acid, the homoallylic

Total synthesis of the macrolide antibiotic 5,6-dihydrocineromycin B

Three building blocks are coupled convergently in the first total synthesis of the macrolide antibiotic 5,6-tetrahydrocineromycin B (1): the facial selective allylation of a methyl ketone is the key step of the synthesis. TBDMS = tert-bytyldimethylsilyl,

First total synthesis and determination of the absolute configuration of the stress factor (+)-hydroxymyoporone

The first total synthesis of the stress factor (+)-hydroxymyoporone (4) is presented. The key step is an asymmetric allylation of the methyl ketone 10 which proceeds with excellent selectivity and yield. In addition, it was proven that the assignment of t