(+/-)-Anisomycin is a potent inhibitor of protein synthesis that is derived from the bacterium Streptomyces griseolus. It acts by blocking the peptidyl transferase center of the 60S ribosomal subunit, thereby preventing the elongation of polypeptide chains. This inhibition of protein synthesis has been shown to induce apoptosis in various cell types, making anisomycin a valuable tool for studying the molecular mechanisms of apoptosis.
Used in Pharmaceutical Research:
(+/-)-Anisomycin is used as a research tool for studying the molecular mechanisms of apoptosis, as it induces apoptosis in various cell types.
Used in Cancer Research:
(+/-)-Anisomycin is used as a potential anti-cancer agent, as it has been shown to inhibit the growth and induce apoptosis in cancer cells.
Used in Signal Transduction Research:
(+/-)-Anisomycin is used as a research tool for studying the stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) pathway and the mitogen-activated protein kinase (MAPK) pathway, as it activates these pathways and leads to the upregulation of various genes involved in stress responses and inflammation.
Used in Pharmaceutical Research:
(+/-)-Anisomycin is used as a research tool for studying the molecular mechanisms of apoptosis, as it induces apoptosis in various cell types.
Used in Cancer Research:
(+/-)-Anisomycin is used as a potential anti-cancer agent, as it has been shown to inhibit the growth and induce apoptosis in cancer cells.
Used in Signal Transduction Research:
(+/-)-Anisomycin is used as a research tool for studying the stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) pathway and the mitogen-activated protein kinase (MAPK) pathway, as it activates these pathways and leads to the upregulation of various genes involved in stress responses and inflammation.
21497-40-5
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Basic information
- Product Name: (+/-)-anisomycin
- Synonyms: (+/-)-anisomycin
- CAS NO:21497-40-5
- Molecular Formula:
- Molecular Weight: 265.309
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (+/-)-anisomycin(CAS DataBase Reference)
- NIST Chemistry Reference: (+/-)-anisomycin(21497-40-5)
- EPA Substance Registry System: (+/-)-anisomycin(21497-40-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 21497-40-5(Hazardous Substances Data)
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21497-40-5 Usage
Check Digit Verification of cas no
The CAS Registry Mumber 21497-40-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,4,9 and 7 respectively; the second part has 2 digits, 4 and 0 respectively.Calculate Digit Verification of CAS Registry Number 21497-40:
(7*2)+(6*1)+(5*4)+(4*9)+(3*7)+(2*4)+(1*0)=105
105 % 10 = 5
So 21497-40-5 is a valid CAS Registry Number.
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21497-40-5Downstream Products
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(+/-)-anisomycin
