215034-81-4

Basic information

• Product Name: 2(1H)-Quinazolinone, 4-(3-chlorophenyl)-6-[2-(4-chlorophenyl)-1,3-dioxolan-2-yl]-
• CAS NO: 215034-81-4
• Molecular Formula: C23H16Cl2N2O3
• Molecular Weight: 439.298
• Mol File: 215034-81-4.mol

Chemical Properties

• CAS DataBase Reference: 2(1H)-Quinazolinone, 4-(3-chlorophenyl)-6-[2-(4-chlorophenyl)-1,3-dioxolan-2-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Quinazolinone, 4-(3-chlorophenyl)-6-[2-(4-chlorophenyl)-1,3-dioxolan-2-yl]-(215034-81-4)
• EPA Substance Registry System: 2(1H)-Quinazolinone, 4-(3-chlorophenyl)-6-[2-(4-chlorophenyl)-1,3-dioxolan-2-yl]-(215034-81-4)

Safety Data

• Hazardous Substances Data: 215034-81-4(Hazardous Substances Data)

Upstream product

• 215034-79-0 [2-amino-5-[2-(4-chlorophenyl)-1,3-dioxolan-2-yl]-phenyl](3-chlorophenyl)methanone 
• 190898-77-2 3-(3-chlorophenyl)-5-[2-(4-chlorophenyl)-1,3-dioxolan-2-yl]-2,1-benzisoxazole 
• 190898-64-7 2-(4-Chlorophenyl)-2-(4-nitrophenyl)-1,3-dioxolane 
• 7497-60-1 (4-Chlorophenyl)(4-nitrophenyl)methanone 
• 766-84-7 3-chloro-benzonitrile 
• 215034-80-3 2,2,2-trichloro-N-{2-(3-chloro-benzoyl)-4-[2-(4-chloro-phenyl)-[1,3]dioxolan-2-yl]-phenyl}-acetamide 

Downstream Products

• 615277-74-2 C₂₃H₁₅Cl₃N₂O₂ 
• 215034-62-1 4-(3-chloro-phenyl)-6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-1-methyl-1H-quinazolin-2-one 
• 215034-65-4 6-[chloro-(4-chloro-phenyl)-(3-methyl-3H-imidazol-4-yl)-methyl]-4-(3-chloro-phenyl)-1-methyl-1H-quinazolin-2-one 
• 215034-86-9 6-(4-chlorobenzoyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinazolinone 
• 215034-82-5 6-(4-chlorobenzoyl)-4-(3-chlorophenyl)-2(1H)-quinazolinone 

Relevant articles and documents

5-Imidazolyl-quinolinones, -quinazolinones and -benzo-azepinones as farnesyltransferase inhibitors

The evaluation of structure-activity relationships associated with the modification of the R115777 quinolinone ring moiety displaying potent in vitro inhibiting activity is described.

Farnesyltransferase inhibiting quinazolinones

This invention concerns compounds of formula the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein the dotted line represents an optional bond; X is oxygen or sulfur; R1and R2eac