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190898-64-7

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190898-64-7 Usage

General Description

2-(4-chlorophenyl)-2-(4-nitrophenyl)-1,3-dioxolane is a chemical compound with a molecular formula C14H10ClNO4. It is a dioxolane derivative consisting of a six-membered dioxolane ring with 4-chlorophenyl and 4-nitrophenyl substituents attached to it. 2-(4-chlorophenyl)-2-(4-nitrophenyl)-1,3-dioxolane is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It may also have potential applications in the field of organic synthesis and medicinal chemistry due to its unique structural properties. Additionally, it may exhibit biological activity and could be used as a starting material for the development of new drugs or pesticides. However, further research and testing are required to fully understand its potential uses and properties.

Check Digit Verification of cas no

The CAS Registry Mumber 190898-64-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,8,9 and 8 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 190898-64:
(8*1)+(7*9)+(6*0)+(5*8)+(4*9)+(3*8)+(2*6)+(1*4)=187
187 % 10 = 7
So 190898-64-7 is a valid CAS Registry Number.

190898-64-7Relevant articles and documents

Streamlined processes for the synthesis of a farnesyl transferase inhibitor drug candidate

Andresen, Brian M.,Couturier, Michel,Cronin, Brian,D'Occhio, Michael,Ewing, Marcus D.,Guinn, Mark,Hawkins, Joel M.,Jasys, V. John,LaGreca, Susan D.,Lyssikatos, Joseph P.,Moraski, Garrett,Ng, Karl,Raggon, Jeffrey W.,Stewart, A. Morgan,Tickner, Derek L.,Tucker, John L.,Urban, Frank J.,Vazquez, Enrique,Wei, Lulin

, p. 643 - 650 (2013/09/02)

As part of a fast-paced oncology program, quinolinone 1 was discovered and developed as a potent inhibitor of farnesyl transferase for the treatment of cancer. The initial synthesis, which suffered from a lengthy linear sequence and a late-stage chromatog

5-Imidazolyl-quinolinones, -quinazolinones and -benzo-azepinones as farnesyltransferase inhibitors

Angibaud, Patrick,Bourdrez, Xavier,Devine, Ann,End, David W.,Freyne, Eddy,Ligny, Yannick,Muller, Philippe,Mannens, Geert,Pilatte, Isabelle,Poncelet, Virginie,Skrzat, Stacy,Smets, Gerda,Van Dun, Jacky,Van Remoortere, Pieter,Venet, Marc,Wouters, Walter

, p. 1543 - 1547 (2007/10/03)

The evaluation of structure-activity relationships associated with the modification of the R115777 quinolinone ring moiety displaying potent in vitro inhibiting activity is described.

Farnesyltransferase inhibiting quinazolinones

-

, (2008/06/13)

This invention concerns compounds of formula the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein the dotted line represents an optional bond; X is oxygen or sulfur; R1and R2eac

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