215160-84-2

Upstream product

• 5848-33-9 2-methyl-4H-pyran-4-one 
• 4799-68-2 3-benzyloxypropan-1-ol 
• 19790-60-4 3-Benzyloxypropanal 
• 215160-79-5 (3S)-5-benzyloxy-3-(4-methoxybenzyloxy)pentanal 
• 215160-81-9 2-[(S)-6-Benzyloxy-2-hydroxy-4-(4-methoxy-benzyloxy)-hexyl]-pyran-4-one 
• 215160-82-0 2-[(S)-6-Benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-hexyl]-pyran-4-one 
• 215160-80-8 1-[(R)-1-(2-Benzyloxy-ethyl)-but-3-enyloxymethyl]-4-methoxy-benzene 
• 100-39-0 benzyl bromide 
• 111322-01-1 (R)-1-benzyloxy-hex-5-en-3-ol 
• 1826-67-1 vinyl magnesium bromide 
• 215160-83-1 (6R,8S)-8-(2-Benzyloxy-ethyl)-10-(tert-butyl-dimethyl-silanyloxy)-1,7-dioxa-spiro[5.5]undec-2-en-4-one 

Downstream Products

• 215160-85-3 (2R,4S,6R,8S)-8-(2-Benzyloxy-ethyl)-10-(tert-butyl-dimethyl-silanyloxy)-4-methyl-2-vinyl-1,7-dioxa-spiro[5.5]undecan-4-ol 
• 215160-86-4 (2S,6S,8R,10S)-2-(2-Benzyloxy-ethyl)-10-hydroxy-10-methyl-8-vinyl-1,7-dioxa-spiro[5.5]undecan-4-one 
• 215160-87-5 (2R,4S,6R,8S,10S)-8-(2-Benzyloxy-ethyl)-4-methyl-2-vinyl-1,7-dioxa-spiro[5.5]undecane-4,10-diol 

Relevant academic research and scientific papers

Synthesis of the AB spiroketal subunit of spongistatin 1 (Altohyrtin A): The pyrone approach

The synthesis of the AB spiroketal fragment of spongistatin 1 (altohyrtin A) has been accomplished utilizing the addition of a metalated pyrone to an aldehyde followed by acid catalyzed spirocyclization. A stereoselective copper (I) promoted conjugate add