Welcome to LookChem.com Sign In|Join Free


  • or


Post Buying Request

215175-83-0 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

215175-83-0 Usage


Methyl 2-(4’-Acetyl-2-fluoro-biphenyl-4-yl)-propionate is a chemical compound characterized as a yellow solid. It is an intermediate in the synthesis process of the metabolite of Flurbiprofen, which is an anti-inflammatory drug commonly used for its analgesic properties.


Used in Pharmaceutical Industry:
Methyl 2-(4’-Acetyl-2-fluoro-biphenyl-4-yl)-propionate is used as a chemical intermediate for the synthesis of the metabolite of Flurbiprofen. This is significant because Flurbiprofen serves as an anti-inflammatory analgesic, making the compound valuable in the development of medications aimed at reducing inflammation and pain.

Check Digit Verification of cas no

The CAS Registry Mumber 215175-83-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,1,7 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 215175-83:
120 % 10 = 0
So 215175-83-0 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017


1.1 GHS Product identifier

Product name methyl 2-[4-(4-acetylphenyl)-3-fluorophenyl]propanoate

1.2 Other means of identification

Product number -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:215175-83-0 SDS

215175-83-0Downstream Products

215175-83-0Relevant articles and documents

Discovery of 4′-OH-flurbiprofen Mannich base derivatives as potential Alzheimer's disease treatment with multiple inhibitory activities

Liu, Hongyan,Qiang, Xiaoming,Song, Qing,Li, Wei,He, Yuxi,Ye, Chanyuan,Tan, Zhenghuai,Deng, Yong

, p. 991 - 1001 (2019)

A series of 4′-OH flurbiprofen Mannich base derivatives were designed, synthesized and evaluated as potential multifunctional agents for the treatment of Alzheimer's disease. The biological screening results indicated that most of these derivatives exhibi

NO-donating tacrine derivatives as potential butyrylcholinesterase inhibitors with vasorelaxation activity

Chen, Yao,Sun, Jianfei,Huang, Zhangjian,Liao, Hong,Peng, Sixun,Lehmann, Jochen,Zhang, Yihua

supporting information, p. 3162 - 3165 (2013/06/27)

To search for potent anti-Alzheimer's disease (AD) agents with multifunctional effects, 12 NO-donating tacrine-flurbiprofen hybrid compounds (2a-l) were synthesized and biologically evaluated. It was found that all the new target compounds showed selective butyrylcholinesterase (BuChE) inhibitory activity in vitro comparable or higher than tacrine and the tacrine-flurbiprofen hybrid compounds 1a-c, and released moderate amount of NO in vitro. The kinetic study suggests that one of the most active and highest BuChE selective compounds 2d may not only compete with the substrate for the same catalytic active site (CAS) but also interact with a second binding site. Furthermore, 2d and 2l exhibited significant vascular relaxation effect, which is beneficial for the treatment of AD. All the results suggest that 2d and 2l might be promising lead compounds for further research.

Isoxazole derivatives


, (2008/06/13)

An isoxazole derivative represented by the formula: or a pharmaceutically acceptable salt thereof useful as a therapeutic drug for auto-immune diseases and inflammatory diseases.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)


What can I do for you?
Get Best Price

Get Best Price for 215175-83-0