215317-20-7 Usage
Uses
Used in Pharmaceutical Industry:
(R)-5-Hydroxy-2-[(S)-1-(3-nitro-phenyl)-propyl]-3-oxo-5-phenethyl-octanoic acid methyl ester is used as a potential candidate for drug development due to its unique combination of functional groups and stereochemistry, which may offer novel therapeutic opportunities.
Used in Chemical Synthesis:
(R)-5-Hydroxy-2-[(S)-1-(3-nitro-phenyl)-propyl]-3-oxo-5-phenethyl-octanoic acid methyl ester is used as a building block or intermediate in the synthesis of more complex molecules, leveraging its diverse functional groups for further chemical reactions and modifications.
Check Digit Verification of cas no
The CAS Registry Mumber 215317-20-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,3,1 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 215317-20:
(8*2)+(7*1)+(6*5)+(5*3)+(4*1)+(3*7)+(2*2)+(1*0)=97
97 % 10 = 7
So 215317-20-7 is a valid CAS Registry Number.
215317-20-7Relevant academic research and scientific papers
A convergent, scalable synthesis of HIV protease inhibitor PNU-140690
Fors, Kristina S.,Gage, James R.,Heier, Richard F.,Kelly, Robert G.,Perrault, William R.,Wicnienski, Nancy
, p. 7348 - 7356 (2007/10/03)
PNU-140690, an inhibitor of the HIV protease enzyme undergoing clinical evaluation as a chemotherapeutic agent for treatment of AIDS, was synthesized by a convergent approach amenable to large-scale preparation in a pilot plant environment. The key step is the aldol addition of nitroaromatic ester (+)-8 to aldehyde 19e. The two stereocenters present in the target molecule were each set independently by resolution of enantiomers. Intermediates along the synthetic routes were chosen to maximize opportunities for isolation and purification by crystallization.
