21560-74-7

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 5653-40-7 2-Amino-4,5-dimethoxybenzoic acid 
• 1609-47-8 diethyl dicarbonate 

Downstream Products

• 81595-15-5 2-(dimethylamino)-6,7-dihydroxy-3,4-dihydroquinazoline hydrobromide 
• 16175-61-4 2-(dimethylamino)-6,7-dimethoxy-4(1H)-quinazolinone 
• 17148-62-8 2-(methylamino)-6,7-dimethoxy-4(1H)-quinazolinone 
• 16175-67-0 2-amino-6,7-dimethoxy-4(1H)-quinazolinone 

Relevant academic research and scientific papers

Guanidinum chloride as dehydrocyclization agent in the synthesis of 2-fuctionalized (4H)-3,1-benzoxazine-4-ones

A facile and expedient route for the synthesis of 2-ethoxy- and 2-(ethylcarboxylate)-(4H)-3,1-benzoxazine-4-ones is described using guanidinium chloride as a safe and convenient dehydrocyclization agent. High yields of the products obtain under mild react

A simple and expedient method for the stepwise synthesis of 2-ethoxy-(4H)-3,1-benzoxazine-4-ones

A simple and practical route is described for the synthesis of 2-ethoxy-(4H)-3,1-benzoxazine-4-ones using the coupling reaction of anthranilic acid derivatives with diethyl dicarbonate following with fast cyclization of the carbamate adduct with a dehydro

Synthesis and biological evaluation of benzamides and benzamidines: Structural requirement of a pyrimidine ring for inhibition of EGFR tyrosine kinase

The benzamides 1 and the benzamidines 2-3 were synthesized as the mimics of 4-anilinoquinazolines, which possess inhibition of epidermal growth factor receptor (EGFR) tyrosine kinase, and tested for cytotoxicity toward A431 and inhibitory activity toward

Novel use for carbamoyl benzoates

Novel alkoxycarbonylamino benzoates and related copounds (carbamoyl benzoates) are disclosed for treatment of auto-immune disease states, such as arthritis.

Synthesis of 2-(Alkylamino)-5,6- and -6,7-dihydroxy-3,4-dihydroquinazolines and Evaluation as Potential Dopamine Agonists

Based upon the known dopaminergic properties of 2-aminodihydroxy-1,2,3,4-tetrahydronaphthalenes (ADTN's), heterocyclic congengers were prepared.Several 2-(alkylamino)-5,6- and -6,7-dihydroxy-3,4-dihydroquinazolines were synthesized and tested for a dopami