2159-48-0

Upstream product

• 28281-76-7 5-methoxyisobenzofuran-1,3-dione 
• 60-29-7 diethyl ether 
• 71-43-2 benzene 
• 53347-55-0 6-methoxy-2,3-diphenyl-1H-indene 
• 586-38-9 3-Methoxybenzoic acid 
• 611-73-4 Benzoylformic acid 
• 27550-59-0 4-hydroxyphthalic anhydride 
• 98-88-4 benzoyl chloride 
• 22921-68-2 2-bromo-5-methoxy-benzoic acid 
• 92152-00-6 2-benzoyl-5-hydroxy-benzoic acid 
• 77-78-1 dimethyl sulfate 
• 849359-07-5 2-benzoyl-5-methoxybenzonitrile 

Downstream Products

• 849359-08-6 methyl [(2-benzoyl-5-methoxybenzoyl)(methyl)amino]acetate 
• 611-94-9 4-Methoxybenzophenone 
• 860444-20-8 4-chloro-6-methoxy-1-phenyl-phthalazine 
• 108618-32-2 6-methoxy-1-phenyl-phthalazine 
• 108620-86-6 7-methoxy-4-phenyl-2H-phthalazin-1-one 

Relevant academic research and scientific papers

A versatile approach for the synthesis of para -substituted arenes via palladium-catalyzed C-H functionalization and protodecarboxylation of benzoic acids

While a great number of ortho C-H functionalization reactions have been developed and several breakthroughs have been achieved in meta C-H activation, para C-H functionalization is still in its infancy stage. In this article, a versatile strategy for the synthesis of para-substituted arenes has been developed via a tandem process consisting of palladium-catalyzed C-H functionalization and subsequent copper-catalyzed protodecarboxylation of benzoic acids. Both electron-withdrawing and electron-donating functionalities can be introduced into the para positions of arenes bearing a variety of substituents.

Palladium-catalyzed chemoselective decarboxylative ortho acylation of benzoic acids with α-oxocarboxylic acids

Palladium-catalyzed chemoselective decarboxylative cross coupling of benzoic acids with α-oxocarboxylic acids was realized via an arene sp 2 C-H functionalization process. This work represents the first example of transition-metal-catalyzed cro

1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF

A 1-amino-phthalazine derivative of general formula (I) wherein the substituents are as defined herein. Also disclosed are a method for preparing such compounds, intermediates for use in such method and medical treatments using the compounds of formula (I

ISOQUINOLINONE POTASSIUM CHANNEL INHIBITORS

The present invention relates to compounds having the structure formula(I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like.

2,3-Diarylindenes and 2,3-diarylindenones: Synthesis, molecular structure, photochemistry, estrogen receptor binding affinity, and comparisons with related triarylethylenes

Two 2,3-diphenylindene and -indenone systems, with potential fluorescent and photofluorogenic properties, were prepared and studied as ligands for the estrogen receptor. The indene systems were prepared by Friedel-Crafts cyclization of appropriate α-benzy