2159-48-0

Basic information

• Product Name: 2-benzoyl-5-methoxybenzoic acid
• CAS NO: 2159-48-0
• Molecular Formula: C₁₅H₁₂O₄
• Molecular Weight: 256.2534
• Mol File: 2159-48-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 477.6°C at 760 mmHg
• Flash Point: 183.5°C
• Density: 1.255g/cm³
• Vapor Pressure: 6.25E-10mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 2-benzoyl-5-methoxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzoyl-5-methoxybenzoic acid(2159-48-0)
• EPA Substance Registry System: 2-benzoyl-5-methoxybenzoic acid(2159-48-0)

Safety Data

• Hazardous Substances Data: 2159-48-0(Hazardous Substances Data)

Upstream product

• 586-38-9 3-Methoxybenzoic acid 
• 611-73-4 Benzoylformic acid 
• 849359-07-5 2-benzoyl-5-methoxybenzonitrile 
• 27550-59-0 4-hydroxyphthalic anhydride 
• 98-88-4 benzoyl chloride 
• 22921-68-2 2-bromo-5-methoxy-benzoic acid 
• 53347-55-0 6-methoxy-2,3-diphenyl-1H-indene 
• 92152-00-6 2-benzoyl-5-hydroxy-benzoic acid 
• 77-78-1 dimethyl sulfate 
• 28281-76-7 5-methoxyisobenzofuran-1,3-dione 
• 60-29-7 diethyl ether 
• 71-43-2 benzene 

Downstream Products

• 611-94-9 4-Methoxybenzophenone 
• 108620-86-6 7-methoxy-4-phenyl-2H-phthalazin-1-one 
• 849359-08-6 methyl [(2-benzoyl-5-methoxybenzoyl)(methyl)amino]acetate 
• 860444-20-8 4-chloro-6-methoxy-1-phenyl-phthalazine 
• 108618-32-2 6-methoxy-1-phenyl-phthalazine 

Relevant articles and documents

A versatile approach for the synthesis of para -substituted arenes via palladium-catalyzed C-H functionalization and protodecarboxylation of benzoic acids

While a great number of ortho C-H functionalization reactions have been developed and several breakthroughs have been achieved in meta C-H activation, para C-H functionalization is still in its infancy stage. In this article, a versatile strategy for the synthesis of para-substituted arenes has been developed via a tandem process consisting of palladium-catalyzed C-H functionalization and subsequent copper-catalyzed protodecarboxylation of benzoic acids. Both electron-withdrawing and electron-donating functionalities can be introduced into the para positions of arenes bearing a variety of substituents.

1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF

A 1-amino-phthalazine derivative of general formula (I) wherein the substituents are as defined herein. Also disclosed are a method for preparing such compounds, intermediates for use in such method and medical treatments using the compounds of formula (I

2,3-Diarylindenes and 2,3-diarylindenones: Synthesis, molecular structure, photochemistry, estrogen receptor binding affinity, and comparisons with related triarylethylenes

Two 2,3-diphenylindene and -indenone systems, with potential fluorescent and photofluorogenic properties, were prepared and studied as ligands for the estrogen receptor. The indene systems were prepared by Friedel-Crafts cyclization of appropriate α-benzy