216019-28-2

Usage

Chemical Properties

Off-white Cryst

Uses

suzuki reaction

InChI:InChI=1/C9H13BO2/c1-7(2)8-4-3-5-9(6-8)10(11)12/h3-7,11-12H,1-2H3

Upstream product

• 5419-55-6 Triisopropyl borate 
• 5433-01-2 1-bromo-3-isopropylbenzene 

Downstream Products

• 853993-37-0 1-(3-isopropylphenyl)-9,10-anthraquinone 
• 540752-75-8 4-chloro-6-(3-isopropyl-phenyl)-pyrimidin-2-ylamine 
• 911814-61-4 1-(3-isopropyl-phenyl)-3-methoxy-1H-indole-2-carboxylic acid ethyl ester 
• 934334-00-6 2,6-bis(3-isopropylphenyl)benzaldehyde 
• 875710-45-5 ethyl 1-(3-isopropylphenyl)-5-trifluoromethyloxy-1H-indole-2-carboxylate 
• 1119899-52-3 4-(5-(3-isopropylphenyl)thiophen-2-yl)quinoline-6-carbaldehyde 
• 1138474-23-3 4-(5-(3-isopropylphenyl)thiophen-2-yl)-5-methyl-N-(4-((2-methyl-1H-imidazol-1-yl)methyl)phenyl)pyrimidin-2-amine 
• 1138472-87-3 {4-[5-(3-isopropyl-phenyl)-thiophen-2-yl]-5-methyl-pyrimidin-2-yl}-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine 
• 1138473-07-0 {4-[5-(3-isopropyl-phenyl)-thiophen-2-yl]-5-methyl-pyrimidin-2-yl}-(4-morpholin-4-yl-phenyl)-amine 
• 1138473-08-1 (4-imidazol-1-yl-phenyl)-{4-[5-(3-isopropyl-phenyl)-thiophen-2-yl]-5-methyl-pyrimidin-2-yl}-amine 
• 1159499-55-4 C₂₄H₃₂N₂O₅ 
• 1208265-77-3 2-chloro-5-(3-isopropyl-phenyl)-pyridine 
• 1221858-41-8 C₁₆H₁₈N₄O₂ 

Relevant academic research and scientific papers

SUBSTITUTED AMINOTETRALINES

The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein R1-R4 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma

Rotation in biphenyls with a single ortho-substituent

Barriers to rotation in a range up to 15.4 kcal mol-1 were determined by dynamic NMR spectroscopy for a series of biphenyl compounds 1a-1h and 2a-2d with a single ortho-substituent. Ab initio calculations reproduce these barriers satisfactorily