216063-12-6

Basic information

• Product Name: 4-Isoxazolecarboxylic acid, 4,5-dihydro-5-(hydroxymethyl)-3-(4-methoxyphenyl)-, ethyl ester, (4R,5R)-
• CAS NO: 216063-12-6
• Molecular Formula: C14H17NO5
• Molecular Weight: 279.293
• Mol File: 216063-12-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Isoxazolecarboxylic acid, 4,5-dihydro-5-(hydroxymethyl)-3-(4-methoxyphenyl)-, ethyl ester, (4R,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolecarboxylic acid, 4,5-dihydro-5-(hydroxymethyl)-3-(4-methoxyphenyl)-, ethyl ester, (4R,5R)-(216063-12-6)
• EPA Substance Registry System: 4-Isoxazolecarboxylic acid, 4,5-dihydro-5-(hydroxymethyl)-3-(4-methoxyphenyl)-, ethyl ester, (4R,5R)-(216063-12-6)

Safety Data

• Hazardous Substances Data: 216063-12-6(Hazardous Substances Data)

Upstream product

• 3717-21-3 p-methoxyl benzaldoxime 
• 10080-68-9 (E)-ethyl 4-hydroxybut-2-enoate 
• 38435-51-7 N-hydroxy-4-methoxy-benzenecarboximidoyl chloride 

Relevant articles and documents

Asymmetric 1,3-dipolar cycloaddition of nitrile oxides generated in situ by direct oxidation of aldoximes

The asymmetric 1,3-dipolar cycloaddition of nitrile oxides, generated in situ from aldoximes by direct oxidation with tert-butyl hypochlorite, to 2-propen-1-ol was achieved by utilizing diisopropyl (R,R)-tartrate as a chiral auxiliary to afford the corresponding (R)-2-isoxazolines with high enantioselectivity up to 96% ee.