216252-56-1

Basic information

• Product Name: N-[2-[4-(2-Isopropoxyphenyl)piperazin-1-yl]ethyl]-2-(2-oxopiperidin-1-yl)acetamide
• Synonyms: RWJ-38063
• CAS NO: 216252-56-1
• Molecular Formula: C₂₂H₃₄N₄O₃
• Molecular Weight: 402.54128
• Mol File: 216252-56-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[2-[4-(2-Isopropoxyphenyl)piperazin-1-yl]ethyl]-2-(2-oxopiperidin-1-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-[4-(2-Isopropoxyphenyl)piperazin-1-yl]ethyl]-2-(2-oxopiperidin-1-yl)acetamide(216252-56-1)
• EPA Substance Registry System: N-[2-[4-(2-Isopropoxyphenyl)piperazin-1-yl]ethyl]-2-(2-oxopiperidin-1-yl)acetamide(216252-56-1)

Safety Data

• Hazardous Substances Data: 216252-56-1(Hazardous Substances Data)

Upstream product

• 216252-67-4 1-(2-phthalimidoethyl)-4-(2-isopropyloxyphenyl)piperazine 
• 216252-69-6 1-t-Butoxycarbonylmethyl-2-piperidone 
• 54013-91-1 2-(1-methylethoxy)phenyl-1-piperazine 
• 675-20-7 piperidin-2-one 
• 72253-28-2 2-(2-oxopiperidin-1-yl)acetic acid 
• 216252-68-5 2-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-ethylamine 

Relevant articles and documents

Novel arylpiperazines as selective α1-adrenergic receptor antagonists

A novel series of arylpiperazines has been synthesized and identified as antagonists of α(1a) adrenergic receptor (α(1a)-AR) implicated in benign prostatic hyperplasia. These compounds selectively bind to membrane bound α(1a)-AR with K(i)s as low as 0.66 nM. As such, these potentially represent a viable treatment for BPH without the side effects associated with known α1-adrenergic antagonists. (C) 2000 Elsevier Science Ltd. All rights reserved.