21633-77-2

Basic information

• Product Name: Propionylmalonic acid diethyl ester
• Synonyms: Propionylmalonic acid diethyl ester;diethyl 2-propionylmalonate
• CAS NO: 21633-77-2
• Molecular Formula: C₁₀H₁₆O₅
• Molecular Weight: 216.23
• Mol File: 21633-77-2.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 262°C at 760 mmHg
• Flash Point: 108.2°C
• Appearance: /
• Density: 1.091g/cm³
• Vapor Pressure: 0.0112mmHg at 25°C
• Refractive Index: 1.437
• PKA: 8.27±0.46(Predicted)
• CAS DataBase Reference: Propionylmalonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propionylmalonic acid diethyl ester(21633-77-2)
• EPA Substance Registry System: Propionylmalonic acid diethyl ester(21633-77-2)

Safety Data

• Hazardous Substances Data: 21633-77-2(Hazardous Substances Data)

Usage

General Description

Propionylmalonic acid diethyl ester is a chemical compound with the molecular formula C11H18O4. It is an ester derivative of propionylmalonic acid, which is commonly used in organic synthesis to create various pharmaceuticals, agrochemicals, and other organic compounds. Propionylmalonic acid diethyl ester is a colorless liquid with a fruity odor, and it is commonly used as a reagent in the production of pharmaceuticals and other organic compounds. It is also used as an intermediate in the synthesis of various organic compounds and is known for its potential as a building block in the development of new drugs and other chemical products. Additionally, it is important to handle this compound with care, as it can be toxic if ingested or inhaled, and it may cause skin and eye irritation upon contact.

InChI:InChI=1/C10H16O5/c1-4-7(11)8(9(12)14-5-2)10(13)15-6-3/h8H,4-6H2,1-3H3

Upstream product

• 996-82-7 sodium diethylmalonate 
• 79-03-8 propionyl chloride 
• 996-82-7 sodium diethylmalonate 
• 109572-65-8 BrMgCH(CO₂Et)2 
• 105-53-3 diethyl malonate 
• 570-08-1 diethyl acetylmalonate 
• 13433-00-6 diethyl aminomalonate hydrochloride 
• 137786-67-5 ethyl 3-amino-2-ethoxycarbonyl-2-butenoate 

Downstream Products

• 13397-87-0 <1-Benzylmercapto-propyliden>-malonsaeure 
• 4949-44-4 ethyl propanoylacetate 
• 865713-68-4 ethyl-4-chloro-6-ethyl-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate 
• 1179343-95-3 1,1-dimethylethyl 4-({5'-[({[6-({[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}amino)-2-pyridinyl]carbonyl}amino)methyl]-2'-fluoro-3-biphenylyl}methyl)-2-methyl-1-piperazinecarboxylate 
• 1179344-22-9 1,1-dimethylethyl (2S)-4-({5'-[({[2-({[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}amino)-5-pyridinyl]carbonyl}amino)methyl]-2'-fluoro-3-biphenylyl}methyl)-2-methyl-1-piperazinecarboxylate 
• 1179343-99-7 3-{[4-({[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}oxy)-1-piperidinyl]carbonyl}benzoic acid 
• 1179344-00-3 methyl 3-{[4-({[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}oxy)-1-piperidinyl]carbonyl}benzoate 
• 1179344-12-7 2-[(2-{[(3-bromo-4-fluorophenyl)methyl]amino}-2-oxoethyl)oxy]-N-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}acetamide 
• 1179344-13-8 2-{[2-({[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}amino)-2-oxoethyl]oxy}-N-[(6-fluoro-3'-formyl-3-biphenylyl)methyl]acetamide 
• 1179344-21-8 6-({[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}amino)-N-[(6-fluoro-3'-{[(3S)-3-methyl-1-piperazinyl]methyl}-3-biphenylyl)methyl]-3-pyridinecarboxamide 
• 1179344-29-6 1,6-diethyl-N-[(6-fluoro-3'-{[(3S)-3-methyl-1-piperazinyl]methyl}-3-biphenylyl)methyl]-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide 
• 1179344-30-9 1,6-diethyl-N-{[6-fluoro-3'-(1-piperazinylmethyl)-3-biphenylyl]methyl}-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide 
• 1179344-52-5 2-{[2-({[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}amino)-2-oxoethyl]oxy}-N-({6-fluoro-3'-[(4-methyl-1-piperazinyl)methyl]-3-biphenylyl}methyl)acetamide 
• 1179344-53-6 2-({2-[({3'-[(4-acetylhexahydro-1H-1,4-diazepin-1-yl)methyl]-6-fluoro-3-biphenylyl}methyl)amino]-2-oxoethyl}oxy)-N-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}acetamide 

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