21635-99-4

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 5-cyano-1H-pyrrole-2-carboxylate is used as a building block for the synthesis of various pharmaceuticals. Its antimicrobial, antifungal, and anticonvulsant properties make it a valuable component in the development of new drugs and treatments.
Used in Agrochemical Industry:
In the agrochemical industry, Ethyl 5-cyano-1H-pyrrole-2-carboxylate is utilized as a building block for the synthesis of various agrochemicals. Its potential biological activities contribute to the development of effective pesticides and other agricultural products.
Used as an Intermediate in Organic Compound Production:
Ethyl 5-cyano-1H-pyrrole-2-carboxylate is also used as an intermediate in the production of other organic compounds. Its versatility in chemical reactions allows for the creation of a wide range of products across different industries.

InChI:InChI=1/C8H8N2O2/c1-2-12-8(11)7-4-3-6(5-9)10-7/h3-4,10H,2H2,1H3

Upstream product

• 1189-71-5 isocyanate de chlorosulfonyle 
• 2199-43-1 ethyl 1H-pyrrole-2-carboxylate 

Downstream Products

• 854044-30-7 5-carboxy-1H-pyrrole-2-carbonitrile 

Relevant academic research and scientific papers

Dissecting the complex recognition interfaces of potent tetrazole- and pyrrole-based anion binders

Tetrazoles are potent anion binders. We report here a new family of tetrazole-pyrrole-amide hosts that arise when a tetrazole is incorporated as a new binding element alongside the well-known amidopyrrole anion-binding scaffold. In addition to reporting three new, modular synthetic routes that can be used to access these structures, we also report that the new hosts are highly potent binders of chloride. Along the way, we carried out studies of a pyrrole ester control compound that, surprisingly, bound anions almost as strongly as did the amide analogues. This led us to investigate further the relative importance of the amide NH in halide binding. We report that, despite the regular appearance of this close amide NH - -Cl contact in calculated and experimental X-ray structures, the amide NH in this family of anion hosts does not hydrogen bond strongly to chloride in solution.

C-fms kinase inhibitors

The invention is directed to compounds of Formulae I: wherein A, R1, R2, R3, R4, X, and W are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase.