216586-10-6Relevant articles and documents
Mechanism-Based Isocoumarin Inhibitors for Human Leukocyte Elastase. Effect of the 7-Amino Substituent and 3-Alkoxy Group in 3-Alkoxy-7-amino-4-chloroisocoumarins on Inhibitory Potency
Kerrigan, John E.,Oleksyszyn, Jozef,Kam, Chih-Min,Selzler, Joe,Powers, James C.
, p. 544 - 552 (2007/10/02)
A series of 3-alkoxy-7-amino-4-chloroisocoumarins with various 3-alkoxy substituents have been prepared and evaluated as inhibitors of human leukocyte elastase (HLE).In addition, a new series of acyl, urea, and carbamate derivatives of 7-amino-4-chloro-3-