21675-11-6

Upstream product

• 14378-06-4 (E)-α-cyanocinnamic acid 
• 100-52-7 benzaldehyde 
• 1011-92-3 2-cyano-3-phenylacrylic acid 

Downstream Products

• 23795-45-1 2-Cyan-3-phenyl-N,N-diaethyl-acrylsaeureamid 
• 100627-04-1 3-phenyl-2-[(1,3,3-trimethyl-indolin-2-yliden)-acetyl]-acrylonitrile 
• 21675-10-5 6-cyano-5-oxo-7-phenyl-2,3,6,7-tetrahydro-5H-thiazolo[3,2-a]pyridine-8-carboxylic acid ethyl ester 
• 117226-93-4 3,5-dicyano-3,4-dihydro-6-methyl-4-phenyl-2(1H)-pyridinone 
• 1121635-81-1 C₂₀H₂₂N₂O₂ 
• 1105675-71-5 N-[2-(3-dimethylaminopropylthio)phenyl]-2-cyanocinnamide 
• 1105675-87-3 N-[2-(2-cyanocinnamoylthio)phenyl]-2-cyanocinnamide 
• 1227562-88-0 Fe(C₅H₄CNCH₃OC(O)CCNCHC₆H₅)2 
• 117226-96-7 3,5-dicyano-6-methyl-4-phenyl-2(1H)-pyridinone 
• 65054-25-3 (Z)-2-Cyano-3-phenyl-acrylic acid 2-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-propyl ester 
• 149651-90-1 methyl 3-cyano-6-methyl-2-oxo-4-phenyl-1,2-dihydropyridine-5-carboxylate 
• 154199-08-3 2-Cyano-3-phenyl-propionyl azide 
• 25695-87-8 Benzyliden-cyanacetanilid 
• 154198-89-7 (E)-2-Cyano-3-phenyl-acryloyl azide 

Relevant academic research and scientific papers

Modular Cyclopentenone Synthesis through the Catalytic Molecular Shuffling of Unsaturated Acid Chlorides and Alkynes

We describe a general strategy for the intermolecular synthesis of polysubstituted cyclopentenones using palladium catalysis. Overall, this reaction is achieved via a molecular shuffling process involving an alkyne, an α,β-unsaturated acid chloride, which serves as both the alkene and carbon monoxide source, and a hydrosilane to create three new C-C bonds. This new carbon monoxide-free pathway delivers the products with excellent yields. Furthermore, the regioselectivity is complementary to conventional methods for cyclopentenone synthesis. In addition, a set of regio- and chemodivergent reactions are presented to emphasize the synthetic potential of this novel strategy.

New esters of vanillin and vanillal with some alkane- and arenecarboxylic acids

Previously unknown esters were synthesized by the reaction of vanillin and vanillal with carboxylic acid chlorides. Pleiades Publishing, Inc., 2006.

Synthesis and transformations of derivatives and analogs of α-cyanocinnamic acid

A reaction of ethyl α-cyanoacetate with 5-arylfurfurals, furfural, and 4-methoxybenzaldehyde in alkaline water medium gives rise to 3-substituted 2-cyanoacrylic acids in high yield. The reaction of the corresponding acyl chlorides with diethylamine and an

α-Isocyanatoacrylonitriles from alkylidene- or arylidenecyanoacetic acids; synthesis and reactions

The Curtius reaction converts alkylidene- or arylidenecyanoacetic acids to α-isocyanatoacrylonitriles in a stereospecific way. These versatile intermediates allow an easy access to arylacetic acids and various amino acid derivatives, as well as β-lactams or 2-azabutadienes.