216854-26-1

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[1-benzoyl-2-(dimethylamino)ethenyl]-
• CAS NO: 216854-26-1
• Molecular Formula: C19H16N2O3
• Molecular Weight: 320.348
• Mol File: 216854-26-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[1-benzoyl-2-(dimethylamino)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[1-benzoyl-2-(dimethylamino)ethenyl]-(216854-26-1)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[1-benzoyl-2-(dimethylamino)ethenyl]-(216854-26-1)

Safety Data

• Hazardous Substances Data: 216854-26-1(Hazardous Substances Data)

Upstream product

• 1074-82-4 potassium phtalimide 
• 1032-67-3 N-benzoylmethylphthalimide 
• 68-12-2 N,N-dimethyl-formamide 
• 532-27-4 1-chloroacetophenone 
• 70-11-1 α-bromoacetophenone 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 216854-35-2 2-(1-Methyl-5-phenyl-1H-pyrazol-4-yl)-isoindole-1,3-dione 
• 216854-29-4 4-phthalimido-1,3-diphenyl-1H-pyrazole 
• 216854-27-2 2-(3-phenyl-1H-pyrazol-4-yl)isoindoline-1,3-dione 
• 216854-39-6 4-amino-1,3-diphenyl-1H-pyrazole 

Relevant articles and documents

1-PYRAZOLO[4,3-C]ISOQUINOLINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

The invention relates to a compound of formula (I), where: R1 is a phenyl group optionally substituted by one or more halogen atoms; R2 is: a hydrogen atom or a halogen atom or a cyano group; a —C(═O)Y group where Y is a hydrogen ato

HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS

The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, solvates thereof, that bind to Inhibitor of Apoptosis Proteins (IAPs). The compounds of the invention may be used as diagnostic and therapeutic agents in the

A convenient one-pot synthesis of 4-amino-3-arylpyrazoles from α- phthaloylaminoacetophenones

Condensation of α-phthaloylaminoacetophenones 1a-c with N,N- dimethylformamide dimethyl acetal afforded the novel enamines 3a-c. Cyclization of 3 with hydrazine, alkylhydrazine or phenylhydrazine salts (4a- d) gave 4-phthaloylamino-3-arylpyrazoles 7-9 in