2169-24-6Relevant academic research and scientific papers
POLYCYCLIC AMIDES AS UBE2K MODULATORS FOR TREATING CANCER
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, (2021/07/10)
Provided are compounds of Formula (I) and pharmaceutically acceptable salts and compositions thereof, which are useful for treating conditions associated with modulation of UBE2K.
An Efficient Synthesis of the Naphthalene Subunits of the Protein Kinase C Inhibitor Calphostin C
Coleman, Robert S.,Grant, Eugene B.
, p. 1357 - 1359 (2007/10/02)
An efficient synthesis of bromonaphthalenes 5b-c, which represent suitably functionalized precursors to the perylenequinone ring system characteristic of the protein kinase C inhibitor calphostin C (1), is described and was based on the Diels-Alder reaction of o-quinol acetate 7 with 1,1,3-trioxygenated butadienes 6a-c, followed by selective, acid-promoted elimination of R3SiOH and AcOH to directly afford naphthalenes 11a-c.
