21709-69-3Relevant academic research and scientific papers
A versatile synthesis of 3-phenylsulfonylpyrroles from α-amino acids
Burley,Hewson
, p. 1151 - 1154 (2007/10/02)
Reaction between α-benzamidoalkyl ketones 4a-e and the vinyl phosphonium salt 1 produces 3-phenylthio-3-pyrrolines 5a-e which can be converted into N-benzyl-3-phenylsulfonyl pyrroles 7a-e by m-CPBA oxidation, diborane reduction and DDQ aromatisation.
AMIDOACETONE ENOLATE ANIONS: ALKYLATION AND MICHAEL REACTION
Hoye, Thomas R.,Duff, Steven R.,King, Rita S.
, p. 3433 - 3436 (2007/10/02)
The lithyum enolate derived from benzamidoacetone (1) can be regiospecifically alkylated at C(1) and stereospecifically added in conjugate fashion to cyclohexenone without resorting to protection of free NH.Comparison is made with alkylations of methyl hippurate.
