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1H-Pyrrole-2,5-dione, 3-(4-chlorophenyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 21724-87-8 Structure
  • Basic information

    1. Product Name: 1H-Pyrrole-2,5-dione, 3-(4-chlorophenyl)-
    2. Synonyms: 3-(4-chloro-phenyl)-pyrrole-2,5-dione;3-(4-Chlor-phenyl)-pyrrol-2,5-dion;N-(p-Chlorphenyl)-maleinimid;
    3. CAS NO:21724-87-8
    4. Molecular Formula: C10H6ClNO2
    5. Molecular Weight: 207.616
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 21724-87-8.mol
  • Chemical Properties

    1. Melting Point: 178 - 180 °C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1H-Pyrrole-2,5-dione, 3-(4-chlorophenyl)-(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1H-Pyrrole-2,5-dione, 3-(4-chlorophenyl)-(21724-87-8)
    11. EPA Substance Registry System: 1H-Pyrrole-2,5-dione, 3-(4-chlorophenyl)-(21724-87-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 21724-87-8(Hazardous Substances Data)

21724-87-8 Usage

Heterocyclic organic compound

The compound contains a pyrrolidinedione core structure, which is a heterocyclic ring consisting of four carbon atoms and one nitrogen atom.

4-chlorophenyl substituent

A chlorine atom is attached to a phenyl group (a six-membered ring with alternating single and double bonds), which is attached to the pyrrolidinedione core.

Pharmaceutical industry use

The compound is commonly used as a building block for the synthesis of various drugs, particularly antipsychotic and anti-inflammatory medications.

Synthesis of organic dyes and pigments

The compound is also utilized in the production of organic dyes and pigments due to its chemical structure and properties.

Potential biological and pharmacological activities

1H-Pyrrole-2,5-dione, 3-(4-chlorophenyl)has been studied for its possible anti-cancer and anti-microbial properties, indicating its potential as a therapeutic agent.

Check Digit Verification of cas no

The CAS Registry Mumber 21724-87-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,7,2 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 21724-87:
(7*2)+(6*1)+(5*7)+(4*2)+(3*4)+(2*8)+(1*7)=98
98 % 10 = 8
So 21724-87-8 is a valid CAS Registry Number.

21724-87-8Downstream Products

21724-87-8Relevant articles and documents

Approach to the Synthesis of Unsymmetrical/Symmetrical Maleimides via Desulfitative Arylation at Different Temperatures

Abbasnia, Masoumeh,Sheykhan, Mehdi,Ghaffari, Tahereh,Safari, Elham

, p. 11688 - 11698 (2020/10/23)

New routes toward selective synthesis of both mono-and diaryl maleimides have been innovated. The mere requirement to this end is through the increase of temperature. The method works effectively for maleic anhydride and maleic acid as well. Also, the fir

Selective and tunable synthesis of 3-arylsuccinimides and 3-arylmaleimides from arenediazonium tetrafluoroborates and maleimides

Yang, Zhen-Hua,Chen, Zhong-Hui,An, Yu-Long,Zhao, Sheng-Yin

, p. 23438 - 23447 (2016/03/12)

A highly efficient synthetic strategy for synthesizing 3-arylsuccinimides has been developed from arenediazonium tetrafluoroborates and maleimides in the presence of TiCl3. The reactions generated 3-arylsuccinimides in satisfactory yields under mild reaction conditions. In addition, 3-arylmaleimides were obtained by the coupling of arenediazonium tetrafluoroborate and maleimides catalyzed by CuCl. This methodology provided the selective and tunable synthesis of two classes of products by simply switching different metal reagents. The methods are simple, efficient and practical.

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