21724-94-7Relevant academic research and scientific papers
Palladium-catalyzed aerobic oxidative carbonylation of alkynes with amines: a general access to substituted maleimides
Yang, Ji,Liu, Jiawang,Jackstell, Ralf,Beller, Matthias
supporting information, p. 10710 - 10713 (2018/09/29)
A catalytic oxidative carbonylation reaction was developed for the synthesis of polysubstituted maleimides from alkynes and amines with air as a green oxidant. This novel transformation proceeds in the presence of palladium chloride without the need for expensive ligands or additives and has a broad substrate scope affording a variety of maleimides in good to high yields.
Palladium-catalyzed direct arylation of maleimides: A simple route to bisaryl-substituted maleimides
Jafarpour, Farnaz,Shamsianpour, Mitra,Issazadeh, Salumeh,Dorrani, Masoumeh,Hazrati, Hamideh
, p. 1668 - 1672 (2017/03/08)
Palladium-catalyzed direct arylation of maleimides via Heck as well as organoboron-mediated Heck-type reactions are developed. These methods offer an approach to a wide variety of biologically interesting 3,4-diarylmaleimide scaffolds from readily accessible starting materials. These approaches led to the feasible one-pot construction of bisaryl-substituted maleimides which have historically been problematic.
Synthesis of 2-arylmaleimides via the Heck reaction
Roshchin, Alexander I.,Polunin, Evgeny V.
experimental part, p. 332 - 333 (2009/05/27)
The Heck reaction of maleimides with aryl iodides in the presence of PdCl2(MeCN)2, Bu4NCl and HCOOK affords the corresponding 2-arylmaleimides in moderate yields.
A facile synthesis of rubrolide E1
Kar, Anirban,Argade, Narshinha P.
, p. 2284 - 2286 (2007/10/03)
A simple and efficient synthesis of rubrolide E (1e) has been demonstrated via Meerwein coupling reaction of para-anisyldiazonium chloride with N-phenylmaleimide (2), regioselective reduction of para-anisylmaleic anhydride (4), Knoevenagel condensation of butyrolactone 5 with para-anisaldehyde and demethylation pathway. Georg Thieme Verlag Stuttgart.
