217439-29-7

Upstream product

• 50-00-0 formaldehyd 
• 20839-80-9 (4-methoxybenzylamino)acetic acid methyl ester 
• 3282-30-2 pivaloyl chloride 
• 217439-25-3 2-Isopropenyl-2-methyl-malonic acid dimethyl ester 

Downstream Products

• 217439-34-4 (2S,3R,4R)-4-Acetyl-3-hydroxy-2-((R)-1-hydroxy-2-methyl-propyl)-1-(4-methoxy-benzyl)-4-methyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester 
• 217439-35-5 (1S,4R,5R)-1-((R)-1-Hydroxy-2-methyl-propyl)-2-(4-methoxy-benzyl)-4-methyl-6-oxa-2-aza-bicyclo[3.2.0]heptane-3,7-dione 
• 155975-72-7 (1S,4R,5R)-1-((S)-1-Hydroxy-2-methyl-propyl)-4-methyl-6-oxa-2-aza-bicyclo[3.2.0]heptane-3,7-dione 
• 155975-72-7 (1S,4R,5R)-1-((R)-1-Hydroxy-2-methyl-propyl)-4-methyl-6-oxa-2-aza-bicyclo[3.2.0]heptane-3,7-dione 
• 217439-31-1 (2S,3R,4R)-4-Acetyl-3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxymethyl-1-(4-methoxy-benzyl)-4-methyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester 
• 217439-30-0 (2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxymethyl-4-isopropenyl-1-(4-methoxy-benzyl)-4-methyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester 
• 217439-32-2 (2R,3R,4R)-4-Acetyl-3-(tert-butyl-dimethyl-silanyloxy)-2-formyl-1-(4-methoxy-benzyl)-4-methyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Enantioselective synthesis of the (5S, 6R, 9R) and (5S, 6R, 9S) analogs of lactacystin β-lactone

The synthesis of two diastereomers of lactacystin β-lactone (2), the β-lactones 3 and 4, is described.