21771-89-1

Usage

Appearance

White to off-white crystalline powder A description of the physical form and color of the compound.

Solubility

Insoluble in water, soluble in organic solvents A property indicating the compound's ability to dissolve in different types of solvents.

Uses

Building block in the synthesis of pharmaceuticals and agrochemicals A specific application of the compound in the production of various drugs and chemicals used in agriculture.

Potential properties

Anti-inflammatory and analgesic Properties being studied for their possible effects in reducing inflammation and relieving pain.

Chemical structure

Phenylacetic acid core with a bromine atom and a phenyl group attached at different positions A description of the compound's molecular arrangement, which contributes to its versatility in the preparation of biologically active compounds.

Versatility

Intermediate for the preparation of various biologically active compounds A property indicating the compound's usefulness in creating other chemical compounds with potential biological activity.

Upstream product

• 75195-67-4 C₁₄H₁₃BrO 
• 33268-46-1 2-(4-bromophenyl)-2-phenylacetonitrile 
• 13391-38-3 4-bromo-benzhydryl chloride 
• 29334-16-5 phenyl(4-bromophenyl)methanol 
• 100-58-3 phenylmagnesium bromide 
• 1122-91-4 4-bromo-benzaldehyde 
• 1070671-69-0 2-(4-bromophenyl)-2-phenyloxirane 
• 90-90-4 (4-bromophenyl)(phenyl)methanone 
• 16343-34-3 2-(4-bromophenyl)-2-phenylethanal 
• 108-86-1 bromobenzene 
• 611-71-2 MANDELIC ACID 

Downstream Products

• 129315-97-5 2-(4-bromophenyl)-2-phenyl-4-pentenoic acid 
• 5359-48-8 methyl 2-(4-bromophenyl)-2-phenylacetate 
• 1061757-61-6 C₂₉H₂₆BrNO 
• 1061757-75-2 C₂₃H₂₂BrNO 
• 1423701-90-9 C₂₁H₁₇BrO₂ 
• 1423700-11-1 methyl 2-phenyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate 
• 1423689-30-8 C₃₄H₂₉ClN₂O₅ 
• 1423689-33-1 C₃₃H₂₇ClN₂O₅ 
• 1423683-47-9 C₃₃H₂₇ClN₂O₅ 
• 1423683-51-5 C₃₃H₂₇ClN₂O₅ 
• 1428526-77-5 diethyl 4-(2-(4-hydroxy-2-(1H-pyrazol-1-yl)pyrimidine-5-ylamino)-2-oxo-1-phenylethyl)phenylphosphonate 
• 1428526-76-4 2-(4-(diethoxyphosphoryl)phenyl)-2-phenylacetic acid 
• 1428526-75-3 diethyl 4-[(methoxycarbonyl)(phenyl)methyl]phenylphosphonate 
• 129315-99-7 trans-(1S^*,2R^*)-2-(4-bromophenyl)-1-methoxy-2-phenylcyclopentane 

Relevant academic research and scientific papers

Efficient transformations of aldehydes and ketones into one-carbon homologated carboxylic acids

Peterson olefination of aldehydes and ketones with trimethylsilyl(methoxy)(benzotriazol-1-yl)methyl anion 6 afforded 1-(benzotriazol-1-yl)-1-methoxyalk-1-enes 7 which were treated without isolation with zinc bromide and hydrochloric acid, to yield the corresponding one-carbon homologated carboxylic acids 4 in good overall yields.

SUBSTITUTED PYRIMIDINES

The present invention relates to substituted pyrimidines useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.

SUBSTITUTED PYRIMIDINES

Disclosed are substituted pyrimidines useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.

LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

Compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or diagnose diseases, disorders, or conditions associated with one or more of the lysophosphatidic acid receptors are provided.

INHIBITORS OF HISTONE DEACETYLASE

This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula compounds of the Formula (I) and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, and racemic and scalemic mixtures, diastereomers and enantiomers thereof, wherein groups L, M, X and Y are as defined herein.

Diastereoselectivity in the reduction of sterically unbiased 2,2-diarylcyclopentanones

Reduction of sterically unbiased 2-phenyl-2-(4-X-phenyl)cyclopentanones 1 (X = NO2, Br, Cl, OCH3, OH, NH2) with either sodium borohydride in methanol or lithium borohydride in tetrahydrofuran at 0°C produced diastereomeric