217816-66-5

Basic information

• Product Name: 3-Bromo-2-fluoro-6-iodobenzonitrile
• Synonyms: 3-Bromo-2-fluoro-6-iodobenzonitrile
• CAS NO: 217816-66-5
• Molecular Formula: C₇H₂BrFIN
• Molecular Weight: 325.9043532
• Mol File: 217816-66-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 299.5±40.0 °C(Predicted)
• Appearance: /
• Density: 2.36±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 3-Bromo-2-fluoro-6-iodobenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-2-fluoro-6-iodobenzonitrile(217816-66-5)
• EPA Substance Registry System: 3-Bromo-2-fluoro-6-iodobenzonitrile(217816-66-5)

Safety Data

• Hazardous Substances Data: 217816-66-5(Hazardous Substances Data)

Upstream product

• 845866-92-4 6-amino-3-bromo-2-fluorobenzonitrile 
• 77326-36-4 2-amino-6-fluorobenzonitrile 
• 217816-54-1 3-bromo-2-fluoro-6-iodo-benzoic acid 
• 136434-77-0 4-bromo-3-fluoroiodobenzene 
• 217816-60-9 3-bromo-2-fluoro-6-iodobenzamide 
• 29632-74-4 2-fluro-4-iodoaniline 
• 348-54-9 2-Fluoroaniline 

Downstream Products

• 935660-95-0 C₁₃H₁₁BrN₄ 

Relevant articles and documents

Synthesis method of 4-bromo-2-cyano-3-fluorobenzoic acid methyl ester

The invention belongs to the technical field of medical intermediates, and particularly relates to a synthetic method of 4-bromo-2-cyano-3-fluorobenzoic acid methyl ester. A compound A is used as an initial raw material, and reacts with N-bromo succinimide to form a compound B, and then through subsequent reactions such as the reaction of the compound B, the 4-bromo-2-cyano-3-fluorobenzoic acid methyl ester is formed. The synthesis method of 4-bromo-2-cyano-3-fluorobenzoic acid methyl ester is put forward for the first time.

METALLO-BETA-LACTAMASE INHIBITORS AND METHODS OF USE THEREOF

The present invention relates to metallo-β-lactamase inhibitor compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein RA, R1, and Z are as defined herein. The present invention also relates to compositions whi

METALLO-BETA-LACTAMASE INHIBITORS

The present invention relates to compounds of formula (I) that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.