218168-22-0Relevant academic research and scientific papers
Asymmetric synthesis of the tetrahydropyran ring, C32-C38 fragment, of phorboxazoles
Brinkmann, Yasmin,Carreno, M. Carmen,Urbano, Antonio,Colobert, Francoise,Solladie, Guy
, p. 4335 - 4338 (2004)
(Chemical Equation Presented) The asymmetric synthesis of a model aldehyde (2R,6R)-2 and the C32-C38 fragment of phorboxazoles, (2R,4R,6R)-1, is described using a sulfoxide as chiral auxiliary. Key advances include the stereoselective reductions of β-keto
A chiral β,δ-dioxo-ε-sulfinyl ester in a convergent enantioselective synthesis towards the C1-C13 polyol fragment of amphotericin B
Solladie, Guy,Wilb, Nicole,Bauder, Claude
, p. 3021 - 3026 (2007/10/03)
This paper describes an efficient stereocontrolled and convergent approach towards the C1-C13 polyol fragment of amphotericin B. The strategy is based on the stereoselective reduction of a chiral β,γ-dioxo- ε-sulfinyl ester to obtain anti-or syn-1,3-diols.
Enantioselective synthesis of C2-symmetric hexols from β-δ- diketosulfoxides
Solladie, Guy,Colobert, Francoise,Denni, Donatienne
, p. 3081 - 3094 (2007/10/03)
An enantioselective synthesis of (1,2S,4S,8S,10S,11)- hexahydroxyundecane, a C2-symmetric hexol precursor of the alkaloid (-)- lythranidine, is described. This convergent synthesis was based on the stereoselective reduction of two different β-δ
